Fulcrum Therapeutics, Inc. (FULC) vs Vanda Pharmaceuticals Inc. (VNDA)
A side-by-side comparison of Fulcrum Therapeutics, Inc. and Vanda Pharmaceuticals Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
FULC
Fulcrum Therapeutics, Inc.
$3.69HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
VNDA
Vanda Pharmaceuticals Inc.
$4.52HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — FULC vs VNDA
growth of $100 · dividends reinvested · last 7yFULC -72.5% (-16.8%/yr)VNDA -65.9% (-14.3%/yr)VNDA compounded faster over this window
FULC VNDA
FULC vs VNDA: by the numbers
- •FULC is the larger company ($282M vs $272M market cap).
- •Both run net losses; FULC's is the smaller (0.00% vs -127.41% net margin).
Metrics side by side
Valuation
| Metric | FULC | VNDA |
|---|---|---|
| P/S ratio | N/A | 1.26 |
| P/B ratio | 0.91 | 1.23 |
Profitability
| Metric | FULC | VNDA |
|---|---|---|
| Gross margin | 0.00% | 92.82% |
| Operating margin | 0.00% | -69.95% |
| Net margin | 0.00% | -127.41% |
| ROE | -27.36% | -124.83% |
| ROIC | -27.62% | -74.73% |
Growth (annualized)
| Metric | FULC | VNDA |
|---|---|---|
| Revenue CAGR (5Y) | N/A | -3.56% |
| Total return CAGR (5Y) | -31.70% | -23.91% |
Frequently asked
- How have FULC and VNDA total returns compared?
- Over the past 5 years, FULC delivered -31.70% and VNDA delivered -23.91% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.