Fulcrum Therapeutics, Inc. (FULC) vs OraSure Technologies, Inc. (OSUR)

A side-by-side comparison of Fulcrum Therapeutics, Inc. and OraSure Technologies, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — FULC vs OSUR

growth of $100 · dividends reinvested · last 7y
FULC -72.5% (-16.8%/yr)OSUR -52.1% (-10.0%/yr)OSUR compounded faster over this window
050100150200Start $100202120232025$27$48
FULC OSUR

FULC vs OSUR: by the numbers

  • •FULC is the larger company ($282M vs $265M market cap).
  • •Both run net losses; FULC's is the smaller (0.00% vs -43.70% net margin).

Metrics side by side

Valuation

MetricFULCOSUR
P/S ratioN/A2.36
P/B ratio0.910.84

Profitability

MetricFULCOSUR
Gross margin0.00%41.38%
Operating margin0.00%-59.23%
Net margin0.00%-43.70%
ROE-27.36%-15.46%
ROIC-27.62%-15.00%

Growth (annualized)

MetricFULCOSUR
Revenue CAGR (5Y)N/A-13.12%
Total return CAGR (5Y)-31.70%-17.56%

Frequently asked

How have FULC and OSUR total returns compared?
Over the past 5 years, FULC delivered -31.70% and OSUR delivered -17.56% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.