4D Molecular Therapeutics, Inc. (FDMT) vs Helus Pharma Inc. (HELP)
A side-by-side comparison of 4D Molecular Therapeutics, Inc. and Helus Pharma Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
FDMT
4D Molecular Therapeutics, Inc.
$12.77HealthcareDelayed quote: Oct 6, 2026, 12:40 PM EDT
HELP
Helus Pharma Inc.
$10.90HealthcareDelayed quote: Oct 6, 2026, 12:40 PM EDT
Total return — FDMT vs HELP
growth of $100 · dividends reinvested · last 1yFDMT +16.6% (+16.6%/yr)HELP +93.2% (+93.2%/yr)HELP compounded faster over this window
FDMT HELP
FDMT vs HELP: by the numbers
- •HELP is the larger company ($676M vs $668M market cap).
- •HELP is profitable (329.09% net margin) while FDMT runs a net loss (-194.74%).
Metrics side by side
Valuation
| Metric | FDMT | HELP |
|---|---|---|
| P/S ratio | 7.26 | N/A |
| P/B ratio | 1.64 | 2.79 |
Profitability
| Metric | FDMT | HELP |
|---|---|---|
| Gross margin | 91.05% | 100.27% |
| Operating margin | -187.24% | 317.06% |
| Net margin | -194.74% | 329.09% |
| ROE | -43.95% | -75.79% |
| ROIC | -44.30% | -73.27% |
Growth (annualized)
| Metric | FDMT | HELP |
|---|---|---|
| Revenue CAGR (5Y) | 31.93% | N/A |
| Total return CAGR (5Y) | -13.08% | N/A |
Frequently asked
- Is FDMT or HELP more profitable?
- HELP runs the higher net margin — FDMT at -194.74% versus HELP at 329.09%.
Go deeper
Dig into the metrics
4D Molecular Therapeutics ROEHelus Pharma ROE4D Molecular Therapeutics operating marginHelus Pharma operating margin4D Molecular Therapeutics revenue growthHelus Pharma revenue growth4D Molecular Therapeutics free cash flowHelus Pharma free cash flow
4D Molecular Therapeutics & Helus Pharma appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.