Is FBIO or PLRX more profitable?

FBIO runs the higher net margin — FBIO at 163.32% versus PLRX at 0.00%.

How have FBIO and PLRX total returns compared?

Over the past 5 years, FBIO delivered -46.06% and PLRX delivered -43.17% annualized total return. Past performance doesn't predict future results.

Fortress Biotech, Inc. (FBIO) vs Pliant Therapeutics, Inc. (PLRX)

A side-by-side comparison of Fortress Biotech, Inc. and Pliant Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

FBIO

Fortress Biotech, Inc.

$68M

$2.05HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT

PLRX

Pliant Therapeutics, Inc.

$63M

$1.02HealthcareDelayed quote: Oct 6, 2026, 12:59 PM EDT

Total return — FBIO vs PLRX

growth of $100 · dividends reinvested · last 6y

FBIO -95.2% (-39.7%/yr)PLRX -95.2% (-39.6%/yr)PLRX compounded faster over this window

FBIO PLRX

FBIO vs PLRX: by the numbers

•FBIO is the larger company ($68M vs $63M market cap).
•FBIO is profitable (163.32% net margin) while PLRX runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	FBIO	PLRX
P/E ratio	0.76	N/A
P/S ratio	0.99	N/A
P/B ratio	0.41	0.43
FCF yield	185.24%	N/A

Profitability

Metric	FBIO	PLRX
Gross margin	62.53%	0.00%
Operating margin	-111.00%	0.00%
Net margin	163.32%	0.00%
ROE	68.12%	-62.81%
ROIC	-10.85%	-56.22%

Growth (annualized)

Metric	FBIO	PLRX
Revenue CAGR (5Y)	5.39%	N/A
Total return CAGR (5Y)	-46.06%	-43.17%

Frequently asked

Is FBIO or PLRX more profitable?: FBIO runs the higher net margin — FBIO at 163.32% versus PLRX at 0.00%.
How have FBIO and PLRX total returns compared?: Over the past 5 years, FBIO delivered -46.06% and PLRX delivered -43.17% annualized total return. Past performance doesn't predict future results.

Go deeper

Full FBIO analysis Full PLRX analysis Interactive comparison tool

Dig into the metrics

Fortress Biotech P/E ratio Fortress Biotech ROE Pliant Therapeutics ROE Fortress Biotech operating margin Pliant Therapeutics operating margin Fortress Biotech revenue growth Pliant Therapeutics revenue growth Fortress Biotech free cash flow Pliant Therapeutics free cash flow

Fortress Biotech & Pliant Therapeutics appear in these rankings

Highest ROE Stocks Highest FCF Yield Stocks Lowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.