Which has grown faster, EXEL or TEM?

Over the past five years, TEM grew revenue faster — EXEL at a 16.06% CAGR versus TEM at 38.24%.

Is EXEL or TEM more profitable?

EXEL runs the higher net margin — EXEL at 35.33% versus TEM at -17.77%.

Exelixis, Inc. (EXEL) vs Tempus AI, Inc. (TEM)

A side-by-side comparison of Exelixis, Inc. and Tempus AI, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

EXEL

Exelixis, Inc.

$14.66B

$58.33HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

TEM

Tempus AI, Inc.

$12.61B

$71.98HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — EXEL vs TEM

growth of $100 · dividends reinvested · last 2y

EXEL +164.6% (+62.7%/yr)TEM +107.6% (+44.1%/yr)EXEL compounded faster over this window

EXEL TEM

EXEL vs TEM: by the numbers

•EXEL is the larger company ($14.66B vs $12.61B market cap).
•EXEL is profitable (35.33% net margin) while TEM runs a net loss (-17.77%).
•TEM grew revenue faster over the past five years (38.24% vs 16.06% CAGR).

Metrics side by side

Valuation

Metric	EXEL	TEM
P/E ratio	18.29	N/A
Forward P/E	16.64	N/A
PEG ratio	0.36	N/A
P/S ratio	6.02	8.81
P/B ratio	7.95	28.34
EV / EBITDA	14.55	N/A
FCF yield	7.90%	N/A

Profitability

Metric	EXEL	TEM
Gross margin	96.48%	63.98%
Operating margin	39.88%	-19.76%
Net margin	35.33%	-17.77%
ROE	46.68%	-57.18%
ROIC	37.87%	-14.34%

Growth (annualized)

Metric	EXEL	TEM
Revenue CAGR (5Y)	16.06%	38.24%
EPS CAGR (5Y)	51.51%	N/A
FCF CAGR (5Y)	39.63%	N/A
Total return CAGR (5Y)	22.79%	N/A

Frequently asked

Which has grown faster, EXEL or TEM?: Over the past five years, TEM grew revenue faster — EXEL at a 16.06% CAGR versus TEM at 38.24%.
Is EXEL or TEM more profitable?: EXEL runs the higher net margin — EXEL at 35.33% versus TEM at -17.77%.

Go deeper

Full EXEL analysis Full TEM analysis Interactive comparison tool

Dig into the metrics

Exelixis P/E ratio Exelixis ROE Tempus AI ROE Exelixis operating margin Tempus AI operating margin Exelixis revenue growth Tempus AI revenue growth Exelixis free cash flow Tempus AI free cash flow

Exelixis & Tempus AI appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.