Which has the lower trailing P/E, EXEL or MEDP?

EXEL has the lower trailing P/E: EXEL trades at 16.95 and MEDP at 36.36. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, EXEL or MEDP?

Over the past five years, MEDP grew revenue faster — EXEL at a 16.06% CAGR versus MEDP at 22.03%.

Is EXEL or MEDP more profitable?

EXEL runs the higher net margin — EXEL at 35.33% versus MEDP at 17.67%.

How have EXEL and MEDP total returns compared?

Over the past 10 years, EXEL delivered 17.26% and MEDP delivered 36.05% annualized total return. Past performance doesn't predict future results.

Exelixis, Inc. (EXEL) vs Medpace Holdings, Inc. (MEDP)

A side-by-side comparison of Exelixis, Inc. and Medpace Holdings, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of August 23, 2026. Differences are shown without an overall score or investment verdict.

EXEL

Exelixis, Inc.

$13.59B

$54.08HealthcareAt close: Aug 21, 2026, 4:00 PM ET

MEDP

Medpace Holdings, Inc.

$17.33B

$620.75HealthcareAt close: Aug 21, 2026, 4:00 PM ET

Total return — EXEL vs MEDP

growth of $100 · dividends reinvested · last 10y

EXEL +409.2% (+17.7%/yr)MEDP +2110.6% (+36.3%/yr)MEDP compounded faster over this window

EXEL MEDP

EXEL vs MEDP: by the numbers

•MEDP is the larger company ($17.33B vs $13.59B market cap).
•EXEL trades at the lower trailing earnings multiple (16.95 vs 36.36 P/E), one valuation lens rather than an overall verdict.
•EXEL converts more revenue to profit (35.33% vs 17.67% net margin).
•MEDP grew revenue faster over the past five years (22.03% vs 16.06% CAGR).

Metrics side by side

Valuation

Metric	EXEL	MEDP
P/E ratio	16.95	36.36
Forward P/E	18.14	35.27
P/S ratio	5.77	6.42
P/B ratio	7.62	41.15
EV / EBITDA	13.93	28.58
FCF yield	8.41%	4.11%

Profitability

Metric	EXEL	MEDP
Gross margin	96.48%	28.76%
Operating margin	39.88%	20.97%
Net margin	35.33%	17.67%
ROE	46.68%	113.29%
ROIC	37.87%	77.00%

Growth (annualized)

Metric	EXEL	MEDP
Revenue CAGR (5Y)	16.06%	22.03%
EPS CAGR (5Y)	51.51%	30.90%
FCF CAGR (5Y)	40.17%	23.40%
Total return CAGR (5Y)	24.00%	28.32%

Frequently asked

Which has the lower trailing P/E, EXEL or MEDP?: EXEL has the lower trailing P/E: EXEL trades at 16.95 and MEDP at 36.36. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, EXEL or MEDP?: Over the past five years, MEDP grew revenue faster — EXEL at a 16.06% CAGR versus MEDP at 22.03%.
Is EXEL or MEDP more profitable?: EXEL runs the higher net margin — EXEL at 35.33% versus MEDP at 17.67%.
How have EXEL and MEDP total returns compared?: Over the past 10 years, EXEL delivered 17.26% and MEDP delivered 36.05% annualized total return. Past performance doesn't predict future results.

Go deeper

Full EXEL analysis Full MEDP analysis Interactive comparison tool

Dig into the metrics

Exelixis P/E ratio Medpace P/E ratio Exelixis ROE Medpace ROE Exelixis operating margin Medpace operating margin Exelixis revenue growth Medpace revenue growth Exelixis free cash flow Medpace free cash flow

Exelixis & Medpace appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified August 23, 2026.