Is EWTX or OPCH more profitable?

OPCH runs the higher net margin — EWTX at 0.00% versus OPCH at 3.68%.

How have EWTX and OPCH total returns compared?

Over the past 5 years, EWTX delivered 16.95% and OPCH delivered -1.37% annualized total return. Past performance doesn't predict future results.

Edgewise Therapeutics, Inc. (EWTX) vs Option Care Health, Inc. (OPCH)

A side-by-side comparison of Edgewise Therapeutics, Inc. and Option Care Health, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

EWTX

Edgewise Therapeutics, Inc.

$4.30B

$39.94HealthcareDelayed quote: Oct 6, 2026, 2:45 PM EDT

OPCH

Option Care Health, Inc.

$4.65B

$31.04HealthcareDelayed quote: Oct 6, 2026, 2:45 PM EDT

Total return — EWTX vs OPCH

growth of $100 · dividends reinvested · last 6y

EWTX +34.3% (+5.0%/yr)OPCH +24.0% (+3.7%/yr)EWTX compounded faster over this window

EWTX OPCH

EWTX vs OPCH: by the numbers

•OPCH is the larger company ($4.65B vs $4.30B market cap).
•OPCH is profitable (3.68% net margin) while EWTX runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	EWTX	OPCH
P/E ratio	N/A	23.33
Forward P/E	N/A	16.51
P/S ratio	N/A	0.82
P/B ratio	9.59	3.69
EV / EBITDA	N/A	13.97

Profitability

Metric	EWTX	OPCH
Gross margin	0.00%	18.17%
Operating margin	0.00%	5.94%
Net margin	0.00%	3.68%
ROE	-44.02%	16.63%
ROIC	-48.57%	9.68%

Growth (annualized)

Metric	EWTX	OPCH
Revenue CAGR (5Y)	N/A	12.17%
Total return CAGR (5Y)	16.95%	-1.37%

Frequently asked

Is EWTX or OPCH more profitable?: OPCH runs the higher net margin — EWTX at 0.00% versus OPCH at 3.68%.
How have EWTX and OPCH total returns compared?: Over the past 5 years, EWTX delivered 16.95% and OPCH delivered -1.37% annualized total return. Past performance doesn't predict future results.

Go deeper

Full EWTX analysis Full OPCH analysis Interactive comparison tool

Dig into the metrics

Option Care Health P/E ratio Edgewise Therapeutics ROE Option Care Health ROE Edgewise Therapeutics operating margin Option Care Health operating margin Edgewise Therapeutics revenue growth Option Care Health revenue growth Edgewise Therapeutics free cash flow Option Care Health free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.