Edgewise Therapeutics, Inc. (EWTX) vs LifeStance Health Group, Inc. (LFST)
A side-by-side comparison of Edgewise Therapeutics, Inc. and LifeStance Health Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
EWTX
Edgewise Therapeutics, Inc.
$40.47HealthcareDelayed quote: Oct 6, 2026, 11:00 AM EDT
LFST
LifeStance Health Group, Inc.
$11.99HealthcareDelayed quote: Oct 6, 2026, 11:00 AM EDT
Total return — EWTX vs LFST
growth of $100 · dividends reinvested · last 5yEWTX +53.6% (+9.0%/yr)LFST -44.2% (-11.0%/yr)EWTX compounded faster over this window
EWTX LFST
EWTX vs LFST: by the numbers
- •LFST is the larger company ($4.65B vs $4.35B market cap).
- •LFST is profitable (3.19% net margin) while EWTX runs a net loss (0.00%).
Metrics side by side
Valuation
| Metric | EWTX | LFST |
|---|---|---|
| P/E ratio | N/A | 92.41 |
| Forward P/E | N/A | 74.66 |
| P/S ratio | N/A | 2.93 |
| P/B ratio | 9.72 | 3.15 |
| EV / EBITDA | N/A | 34.76 |
| FCF yield | N/A | 3.74% |
Profitability
| Metric | EWTX | LFST |
|---|---|---|
| Gross margin | 0.00% | 33.56% |
| Operating margin | 0.00% | 4.95% |
| Net margin | 0.00% | 3.19% |
| ROE | -44.02% | 3.43% |
| ROIC | -48.57% | 3.03% |
Growth (annualized)
| Metric | EWTX | LFST |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 24.79% |
| Total return CAGR (5Y) | 16.95% | -1.46% |
Frequently asked
- Is EWTX or LFST more profitable?
- LFST runs the higher net margin — EWTX at 0.00% versus LFST at 3.19%.
- How have EWTX and LFST total returns compared?
- Over the past 5 years, EWTX delivered 16.95% and LFST delivered -1.46% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
LifeStance Health P/E ratioEdgewise Therapeutics ROELifeStance Health ROEEdgewise Therapeutics operating marginLifeStance Health operating marginEdgewise Therapeutics revenue growthLifeStance Health revenue growthEdgewise Therapeutics free cash flowLifeStance Health free cash flow
Edgewise Therapeutics & LifeStance Health appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.