Is ETON or GHRS more profitable?

ETON runs the higher net margin — ETON at 12.02% versus GHRS at 0.00%.

How have ETON and GHRS total returns compared?

Over the past 5 years, ETON delivered 63.04% and GHRS delivered 0.52% annualized total return. Past performance doesn't predict future results.

Eton Pharmaceuticals, Inc. (ETON) vs GH Research PLC (GHRS)

A side-by-side comparison of Eton Pharmaceuticals, Inc. and GH Research PLC across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

ETON

Eton Pharmaceuticals, Inc.

$1.50B

$54.67HealthcareDelayed quote: Oct 6, 2026, 10:10 AM EDT

GHRS

GH Research PLC

$1.49B

$21.77HealthcareDelayed quote: Oct 6, 2026, 10:10 AM EDT

Total return — ETON vs GHRS

growth of $100 · dividends reinvested · last 5y

ETON +814.8% (+55.7%/yr)GHRS +15.2% (+2.9%/yr)ETON compounded faster over this window

Log scale — wide-divergence pair

ETON GHRS

ETON vs GHRS: by the numbers

•ETON is the larger company ($1.50B vs $1.49B market cap).
•ETON is profitable (12.02% net margin) while GHRS runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	ETON	GHRS
P/E ratio	142.15	N/A
Forward P/E	50.27	N/A
P/S ratio	14.18	N/A
P/B ratio	32.15	4.15
EV / EBITDA	71.92	N/A
FCF yield	0.98%	N/A

Profitability

Metric	ETON	GHRS
Gross margin	57.87%	0.00%
Operating margin	0.09%	0.00%
Net margin	12.02%	0.00%
ROE	27.24%	-17.32%
ROIC	20.41%	-19.87%

Growth (annualized)

Metric	ETON	GHRS
Revenue CAGR (5Y)	47.98%	N/A
Total return CAGR (5Y)	63.04%	0.52%

Frequently asked

Is ETON or GHRS more profitable?: ETON runs the higher net margin — ETON at 12.02% versus GHRS at 0.00%.
How have ETON and GHRS total returns compared?: Over the past 5 years, ETON delivered 63.04% and GHRS delivered 0.52% annualized total return. Past performance doesn't predict future results.

Go deeper

Full ETON analysis Full GHRS analysis Interactive comparison tool

Dig into the metrics

Eton Pharmaceuticals P/E ratio Eton Pharmaceuticals ROE GH Research ROE Eton Pharmaceuticals operating margin GH Research operating margin Eton Pharmaceuticals revenue growth GH Research revenue growth Eton Pharmaceuticals free cash flow GH Research free cash flow

Eton Pharmaceuticals & GH Research appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.