Establishment Labs Holdings Inc. (ESTA) vs Vir Biotechnology, Inc. (VIR)
A side-by-side comparison of Establishment Labs Holdings Inc. and Vir Biotechnology, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ESTA
Establishment Labs Holdings Inc.
$65.29HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
VIR
Vir Biotechnology, Inc.
$11.60HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Total return — ESTA vs VIR
growth of $100 · dividends reinvested · last 7yESTA +283.8% (+21.2%/yr)VIR -16.0% (-2.5%/yr)ESTA compounded faster over this window
ESTA VIR
ESTA vs VIR: by the numbers
- •VIR is the larger company ($1.96B vs $1.92B market cap).
- •Both run net losses; ESTA's is the smaller (-15.82% vs -83.00% net margin).
- •ESTA grew revenue faster over the past five years (17.02% vs 11.22% CAGR).
Metrics side by side
Valuation
| Metric | ESTA | VIR |
|---|---|---|
| P/S ratio | 7.82 | 6.45 |
| P/B ratio | 88.93 | 1.99 |
Profitability
| Metric | ESTA | VIR |
|---|---|---|
| Gross margin | 70.49% | 82.92% |
| Operating margin | -18.48% | -682.68% |
| Net margin | -15.82% | -83.00% |
| ROE | -179.99% | -25.62% |
| ROIC | -6.53% | -24.09% |
Growth (annualized)
| Metric | ESTA | VIR |
|---|---|---|
| Revenue CAGR (5Y) | 17.02% | 11.22% |
| Total return CAGR (5Y) | -1.56% | -19.71% |
Frequently asked
- Which has grown faster, ESTA or VIR?
- Over the past five years, ESTA grew revenue faster — ESTA at a 17.02% CAGR versus VIR at 11.22%.
- How have ESTA and VIR total returns compared?
- Over the past 5 years, ESTA delivered -1.56% and VIR delivered -19.71% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Establishment Labs ROEVir Biotechnology ROEEstablishment Labs operating marginVir Biotechnology operating marginEstablishment Labs revenue growthVir Biotechnology revenue growthEstablishment Labs free cash flowVir Biotechnology free cash flow
Establishment Labs & Vir Biotechnology appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.