Establishment Labs Holdings Inc. (ESTA) vs Trevi Therapeutics, Inc. (TRVI)
A side-by-side comparison of Establishment Labs Holdings Inc. and Trevi Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ESTA
Establishment Labs Holdings Inc.
$65.28HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT
TRVI
Trevi Therapeutics, Inc.
$13.28HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT
Total return — ESTA vs TRVI
growth of $100 · dividends reinvested · last 7yESTA +155.8% (+14.4%/yr)TRVI +73.9% (+8.2%/yr)ESTA compounded faster over this window
ESTA TRVI
ESTA vs TRVI: by the numbers
- •ESTA is the larger company ($1.92B vs $1.88B market cap).
- •Both run net losses; TRVI's is the smaller (0.00% vs -15.82% net margin).
Metrics side by side
Valuation
| Metric | ESTA | TRVI |
|---|---|---|
| P/S ratio | 7.82 | N/A |
| P/B ratio | 88.92 | 5.86 |
Profitability
| Metric | ESTA | TRVI |
|---|---|---|
| Gross margin | 70.49% | 0.00% |
| Operating margin | -18.48% | 0.00% |
| Net margin | -15.82% | 0.00% |
| ROE | -179.99% | -15.90% |
| ROIC | -6.53% | -18.51% |
Growth (annualized)
| Metric | ESTA | TRVI |
|---|---|---|
| Revenue CAGR (5Y) | 17.02% | N/A |
| Total return CAGR (5Y) | -1.56% | 61.74% |
Frequently asked
- How have ESTA and TRVI total returns compared?
- Over the past 5 years, ESTA delivered -1.56% and TRVI delivered 61.74% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Establishment Labs ROETrevi Therapeutics ROEEstablishment Labs operating marginTrevi Therapeutics operating marginEstablishment Labs revenue growthTrevi Therapeutics revenue growthEstablishment Labs free cash flowTrevi Therapeutics free cash flow
Establishment Labs & Trevi Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.