Establishment Labs Holdings Inc. (ESTA) vs Mineralys Therapeutics, Inc. (MLYS)
A side-by-side comparison of Establishment Labs Holdings Inc. and Mineralys Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ESTA
Establishment Labs Holdings Inc.
$64.88HealthcareDelayed quote: Oct 6, 2026, 12:55 PM EDT
MLYS
Mineralys Therapeutics, Inc.
$22.39HealthcareDelayed quote: Oct 6, 2026, 12:55 PM EDT
Total return — ESTA vs MLYS
growth of $100 · dividends reinvested · last 4yESTA -2.2% (-0.6%/yr)MLYS +26.4% (+6.0%/yr)MLYS compounded faster over this window
ESTA MLYS
ESTA vs MLYS: by the numbers
- •MLYS is the larger company ($1.97B vs $1.91B market cap).
- •Both run net losses; MLYS's is the smaller (0.00% vs -15.82% net margin).
Metrics side by side
Valuation
| Metric | ESTA | MLYS |
|---|---|---|
| P/S ratio | 7.77 | N/A |
| P/B ratio | 88.37 | 3.58 |
Profitability
| Metric | ESTA | MLYS |
|---|---|---|
| Gross margin | 70.49% | 0.00% |
| Operating margin | -18.48% | 0.00% |
| Net margin | -15.82% | 0.00% |
| ROE | -179.99% | -63.45% |
| ROIC | -6.53% | -57.17% |
Growth (annualized)
| Metric | ESTA | MLYS |
|---|---|---|
| Revenue CAGR (5Y) | 17.02% | N/A |
| Total return CAGR (5Y) | -1.56% | N/A |
Go deeper
Dig into the metrics
Establishment Labs ROEMineralys Therapeutics ROEEstablishment Labs operating marginMineralys Therapeutics operating marginEstablishment Labs revenue growthMineralys Therapeutics revenue growthEstablishment Labs free cash flowMineralys Therapeutics free cash flow
Establishment Labs & Mineralys Therapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.