Establishment Labs Holdings Inc. (ESTA) vs Inspire Medical Systems, Inc. (INSP)
A side-by-side comparison of Establishment Labs Holdings Inc. and Inspire Medical Systems, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
ESTA
Establishment Labs Holdings Inc.
$65.51HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
INSP
Inspire Medical Systems, Inc.
$69.40HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
Total return — ESTA vs INSP
growth of $100 · dividends reinvested · last 8yESTA +168.6% (+13.1%/yr)INSP +60.9% (+6.1%/yr)ESTA compounded faster over this window
ESTA INSP
ESTA vs INSP: by the numbers
- •INSP is the larger company ($2.01B vs $1.93B market cap).
- •INSP is profitable (15.03% net margin) while ESTA runs a net loss (-15.82%).
- •INSP grew revenue faster over the past five years (38.69% vs 17.02% CAGR).
Metrics side by side
Valuation
| Metric | ESTA | INSP |
|---|---|---|
| P/E ratio | N/A | 15.02 |
| Forward P/E | N/A | 58.11 |
| P/S ratio | 7.84 | 2.23 |
| P/B ratio | 89.24 | 2.43 |
| EV / EBITDA | N/A | 26.75 |
| FCF yield | N/A | 5.84% |
Profitability
| Metric | ESTA | INSP |
|---|---|---|
| Gross margin | 70.49% | 86.13% |
| Operating margin | -18.48% | 6.02% |
| Net margin | -15.82% | 15.03% |
| ROE | -179.99% | 16.36% |
| ROIC | -6.53% | 6.33% |
Growth (annualized)
| Metric | ESTA | INSP |
|---|---|---|
| Revenue CAGR (5Y) | 17.02% | 38.69% |
| Total return CAGR (5Y) | -1.56% | -21.38% |
Frequently asked
- Which has grown faster, ESTA or INSP?
- Over the past five years, INSP grew revenue faster — ESTA at a 17.02% CAGR versus INSP at 38.69%.
- Is ESTA or INSP more profitable?
- INSP runs the higher net margin — ESTA at -15.82% versus INSP at 15.03%.
- How have ESTA and INSP total returns compared?
- Over the past 5 years, ESTA delivered -1.56% and INSP delivered -21.38% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Inspire Medical Systems P/E ratioEstablishment Labs ROEInspire Medical Systems ROEEstablishment Labs operating marginInspire Medical Systems operating marginEstablishment Labs revenue growthInspire Medical Systems revenue growthEstablishment Labs free cash flowInspire Medical Systems free cash flow
Establishment Labs & Inspire Medical Systems appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.