Enanta Pharmaceuticals, Inc. (ENTA) vs Orthofix Medical Inc. (OFIX)

A side-by-side comparison of Enanta Pharmaceuticals, Inc. and Orthofix Medical Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — ENTA vs OFIX

growth of $100 · dividends reinvested · last 10y
ENTA -51.4% (-7.0%/yr)OFIX -77.1% (-13.7%/yr)ENTA compounded faster over this window
0100200300400500Start $10020182020202220242026$49$23
ENTA OFIX

ENTA vs OFIX: by the numbers

  • •OFIX is the larger company ($380M vs $354M market cap).
  • •Both run net losses; OFIX's is the smaller (-7.41% vs -96.89% net margin).
  • •OFIX grew revenue faster over the past five years (12.83% vs -7.65% CAGR).

Metrics side by side

Valuation

MetricENTAOFIX
P/S ratio5.420.46
P/B ratio3.500.89
EV / EBITDAN/A4.27

Profitability

MetricENTAOFIX
Gross margin98.15%69.59%
Operating margin-130.65%-3.05%
Net margin-96.89%-7.41%
ROE-62.56%-14.38%
ROIC-24.20%-3.55%

Growth (annualized)

MetricENTAOFIX
Revenue CAGR (5Y)-7.65%12.83%
Total return CAGR (5Y)-26.94%-23.97%

Frequently asked

Which has grown faster, ENTA or OFIX?
Over the past five years, OFIX grew revenue faster — ENTA at a -7.65% CAGR versus OFIX at 12.83%.
How have ENTA and OFIX total returns compared?
Over the past 10 years, ENTA delivered -7.11% and OFIX delivered -13.51% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.