Editas Medicine, Inc. (EDIT) vs Shoulder Innovations, Inc. (SI)

A side-by-side comparison of Editas Medicine, Inc. and Shoulder Innovations, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

EDIT

Editas Medicine, Inc.

$419M

$2.73HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Shoulder Innovations, Inc.

$397M

$19.14HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — EDIT vs SI

growth of $100 · dividends reinvested · last 1y

EDIT +10.7% (+10.7%/yr)SI +30.2% (+30.2%/yr)SI compounded faster over this window

EDIT SI

EDIT vs SI: by the numbers

•EDIT is the larger company ($419M vs $397M market cap).
•Both run net losses; SI's is the smaller (-58.33% vs -157.32% net margin).

Metrics side by side

Valuation

Metric	EDIT	SI
P/S ratio	8.91	6.61
P/B ratio	3.98	3.19

Profitability

Metric	EDIT	SI
Gross margin	100.00%	77.34%
Operating margin	-245.15%	-58.53%
Net margin	-157.32%	-58.33%
ROE	-70.24%	-28.18%
ROIC	-48.61%	-25.26%

Growth (annualized)

Metric	EDIT	SI
Revenue CAGR (5Y)	-10.34%	N/A
Total return CAGR (5Y)	-40.76%	N/A

Go deeper

Full EDIT analysis Full SI analysis Interactive comparison tool

Dig into the metrics

Editas Medicine ROE Shoulder Innovations ROE Editas Medicine operating margin Shoulder Innovations operating margin Editas Medicine revenue growth Shoulder Innovations revenue growth Editas Medicine free cash flow Shoulder Innovations free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.