Dyne Therapeutics, Inc. (DYN) vs TransMedics Group, Inc. (TMDX)

A side-by-side comparison of Dyne Therapeutics, Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Dyne Therapeutics, Inc. logo
DYN
Dyne Therapeutics, Inc.
$2.83B
$15.16HealthcareDelayed quote: Oct 6, 2026, 10:05 AM EDT
TransMedics Group, Inc. logo
TMDX
TransMedics Group, Inc.
$2.83B
$81.92HealthcareDelayed quote: Oct 6, 2026, 10:05 AM EDT

Total return — DYN vs TMDX

growth of $100 · dividends reinvested · last 6y
DYN -35.4% (-7.0%/yr)TMDX +403.6% (+30.9%/yr)TMDX compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $100202120222023202420252026$65$504
DYN TMDX

DYN vs TMDX: by the numbers

  • •DYN is the larger company ($2.83B vs $2.83B market cap).
  • •TMDX is profitable (22.69% net margin) while DYN runs a net loss (0.00%).

Metrics side by side

Valuation

MetricDYNTMDX
P/E ratioN/A21.22
Forward P/EN/A55.84
P/S ratioN/A4.24
P/B ratio4.035.46
EV / EBITDAN/A27.33
FCF yieldN/A2.79%

Profitability

MetricDYNTMDX
Gross margin0.00%58.69%
Operating margin0.00%12.21%
Net margin0.00%22.69%
ROE-73.97%29.28%
ROIC-58.28%5.87%

Growth (annualized)

MetricDYNTMDX
Revenue CAGR (5Y)N/A86.12%
Total return CAGR (5Y)-0.38%21.77%

Frequently asked

Is DYN or TMDX more profitable?
TMDX runs the higher net margin — DYN at 0.00% versus TMDX at 22.69%.
How have DYN and TMDX total returns compared?
Over the past 5 years, DYN delivered -0.38% and TMDX delivered 21.77% annualized total return. Past performance doesn't predict future results.

Go deeper

Full DYN analysisFull TMDX analysisInteractive comparison tool

Dig into the metrics

TransMedics P/E ratioDyne Therapeutics ROETransMedics ROEDyne Therapeutics operating marginTransMedics operating marginDyne Therapeutics revenue growthTransMedics revenue growthDyne Therapeutics free cash flowTransMedics free cash flow

Dyne Therapeutics & TransMedics appear in these rankings

Fastest Revenue Growth StocksHighest ROE Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.