Design Therapeutics, Inc. (DSGN) vs Sana Biotechnology, Inc. (SANA)

A side-by-side comparison of Design Therapeutics, Inc. and Sana Biotechnology, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — DSGN vs SANA

growth of $100 · dividends reinvested · last 6y
DSGN -70.1% (-18.2%/yr)SANA -90.6% (-32.5%/yr)DSGN compounded faster over this window
020406080100Start $10020222023202420252026$30$9
DSGN SANA

DSGN vs SANA: by the numbers

  • •SANA is the larger company ($765M vs $748M market cap).

Metrics side by side

Valuation

MetricDSGNSANA
P/B ratio3.704.95

Profitability

MetricDSGNSANA
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin0.00%0.00%
ROE-35.07%-137.04%
ROIC-38.92%-67.58%

Growth (annualized)

MetricDSGNSANA
Total return CAGR (5Y)-3.82%-32.33%

Frequently asked

How have DSGN and SANA total returns compared?
Over the past 5 years, DSGN delivered -3.82% and SANA delivered -32.33% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.