Bright Minds Biosciences Inc. (DRUG) vs Puma Biotechnology, Inc. (PBYI)

A side-by-side comparison of Bright Minds Biosciences Inc. and Puma Biotechnology, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Bright Minds Biosciences Inc. logo
DRUG
Bright Minds Biosciences Inc.
$470M
$48.02HealthcareDelayed quote: Oct 6, 2026, 12:25 PM EDT
Puma Biotechnology, Inc. logo
PBYI
Puma Biotechnology, Inc.
$487M
$9.56HealthcareDelayed quote: Oct 6, 2026, 12:24 PM EDT

Total return — DRUG vs PBYI

growth of $100 · dividends reinvested · last 6y
DRUG +84.4% (+10.7%/yr)PBYI -11.6% (-2.0%/yr)DRUG compounded faster over this window
0100200300Start $10020222023202420252026$184$88
DRUG PBYI

DRUG vs PBYI: by the numbers

  • •PBYI is the larger company ($487M vs $470M market cap).
  • •PBYI is profitable (11.55% net margin) while DRUG runs a net loss (0.00%).

Metrics side by side

Valuation

MetricDRUGPBYI
P/E ratioN/A18.52
Forward P/EN/A25.16
P/S ratioN/A2.10
P/B ratio2.173.51
EV / EBITDAN/A10.48
FCF yieldN/A8.44%

Profitability

MetricDRUGPBYI
Gross margin0.00%74.83%
Operating margin0.00%13.16%
Net margin0.00%11.55%
ROE-8.21%19.28%
ROIC-13.15%18.26%

Growth (annualized)

MetricDRUGPBYI
Revenue CAGR (5Y)N/A0.29%
FCF CAGR (5Y)N/A90.51%
Total return CAGR (5Y)6.76%9.26%

Frequently asked

Is DRUG or PBYI more profitable?
PBYI runs the higher net margin — DRUG at 0.00% versus PBYI at 11.55%.
How have DRUG and PBYI total returns compared?
Over the past 5 years, DRUG delivered 6.76% and PBYI delivered 9.26% annualized total return. Past performance doesn't predict future results.

Go deeper

Full DRUG analysisFull PBYI analysisInteractive comparison tool

Dig into the metrics

Puma Biotechnology P/E ratioBright Minds Biosciences ROEPuma Biotechnology ROEBright Minds Biosciences operating marginPuma Biotechnology operating marginBright Minds Biosciences revenue growthPuma Biotechnology revenue growthBright Minds Biosciences free cash flowPuma Biotechnology free cash flow

Bright Minds Biosciences & Puma Biotechnology appear in these rankings

Highest ROIC StocksHighest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.