Denali Therapeutics Inc. (DNLI) vs MBX Biosciences, Inc. Common Stock (MBX)

A side-by-side comparison of Denali Therapeutics Inc. and MBX Biosciences, Inc. Common Stock across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Denali Therapeutics Inc. logo
DNLI
Denali Therapeutics Inc.
$3.06B
$19.28HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
MBX Biosciences, Inc. Common Stock logo
MBX
MBX Biosciences, Inc. Common Stock
$2.71B
$56.92HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — DNLI vs MBX

growth of $100 · dividends reinvested · last 2y
DNLI -26.5% (-14.3%/yr)MBX +147.5% (+57.3%/yr)MBX compounded faster over this window
100200300Start $10020252026$74$248
DNLI MBX

DNLI vs MBX: by the numbers

  • •DNLI is the larger company ($3.06B vs $2.71B market cap).
  • •Both run net losses; MBX's is the smaller (0.00% vs -14191.20% net margin).

Metrics side by side

Valuation

MetricDNLIMBX
P/S ratio849.04N/A
P/B ratio3.666.62

Profitability

MetricDNLIMBX
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin-14191.20%0.00%
ROE-61.24%-25.47%
ROIC-50.82%-28.60%

Growth (annualized)

MetricDNLIMBX
Revenue CAGR (5Y)20.68%N/A
Total return CAGR (5Y)-16.91%N/A

Go deeper

Full DNLI analysisFull MBX analysisInteractive comparison tool

Dig into the metrics

Denali Therapeutics ROEMBX Biosciences, Inc. Common Stock ROEDenali Therapeutics operating marginMBX Biosciences, Inc. Common Stock operating marginDenali Therapeutics revenue growthMBX Biosciences, Inc. Common Stock revenue growthDenali Therapeutics free cash flowMBX Biosciences, Inc. Common Stock free cash flow

Denali Therapeutics & MBX Biosciences, Inc. Common Stock appear in these rankings

Fastest Revenue Growth Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.