Is DFTX or OPCH more profitable?

OPCH runs the higher net margin — DFTX at 0.00% versus OPCH at 3.68%.

How have DFTX and OPCH total returns compared?

Over the past 5 years, DFTX delivered 1.43% and OPCH delivered -1.37% annualized total return. Past performance doesn't predict future results.

Definium Therapeutics, Inc. (DFTX) vs Option Care Health, Inc. (OPCH)

A side-by-side comparison of Definium Therapeutics, Inc. and Option Care Health, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

DFTX

Definium Therapeutics, Inc.

$4.67B

$35.21HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT

OPCH

Option Care Health, Inc.

$4.65B

$31.04HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT

Total return — DFTX vs OPCH

growth of $100 · dividends reinvested · last 10y

DFTX +971.9% (+26.8%/yr)OPCH +123.9% (+8.4%/yr)DFTX compounded faster over this window

DFTX OPCH

DFTX vs OPCH: by the numbers

•DFTX is the larger company ($4.67B vs $4.65B market cap).
•OPCH is profitable (3.68% net margin) while DFTX runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	DFTX	OPCH
P/E ratio	N/A	23.33
Forward P/E	N/A	16.51
P/S ratio	N/A	0.82
P/B ratio	5.09	3.69
EV / EBITDA	N/A	13.97

Profitability

Metric	DFTX	OPCH
Gross margin	0.00%	18.17%
Operating margin	0.00%	5.94%
Net margin	0.00%	3.68%
ROE	-38.51%	16.63%
ROIC	-23.81%	9.68%

Growth (annualized)

Metric	DFTX	OPCH
Revenue CAGR (5Y)	N/A	12.17%
Total return CAGR (5Y)	1.43%	-1.37%

Frequently asked

Is DFTX or OPCH more profitable?: OPCH runs the higher net margin — DFTX at 0.00% versus OPCH at 3.68%.
How have DFTX and OPCH total returns compared?: Over the past 5 years, DFTX delivered 1.43% and OPCH delivered -1.37% annualized total return. Past performance doesn't predict future results.

Go deeper

Full DFTX analysis Full OPCH analysis Interactive comparison tool

Dig into the metrics

Option Care Health P/E ratio Definium Therapeutics ROE Option Care Health ROE Definium Therapeutics operating margin Option Care Health operating margin Definium Therapeutics revenue growth Option Care Health revenue growth Definium Therapeutics free cash flow Option Care Health free cash flow

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.