Definium Therapeutics, Inc. (DFTX) vs LifeStance Health Group, Inc. (LFST)
A side-by-side comparison of Definium Therapeutics, Inc. and LifeStance Health Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
DFTX
Definium Therapeutics, Inc.
$34.98HealthcareDelayed quote: Oct 6, 2026, 10:25 AM EDT
LFST
LifeStance Health Group, Inc.
$11.96HealthcareDelayed quote: Oct 6, 2026, 10:25 AM EDT
Total return — DFTX vs LFST
growth of $100 · dividends reinvested · last 5yDFTX -34.9% (-8.2%/yr)LFST -44.2% (-11.0%/yr)DFTX compounded faster over this window
DFTX LFST
DFTX vs LFST: by the numbers
- •DFTX is the larger company ($4.64B vs $4.64B market cap).
- •LFST is profitable (3.19% net margin) while DFTX runs a net loss (0.00%).
Metrics side by side
Valuation
| Metric | DFTX | LFST |
|---|---|---|
| P/E ratio | N/A | 92.24 |
| Forward P/E | N/A | 74.53 |
| P/S ratio | N/A | 2.93 |
| P/B ratio | 5.05 | 3.14 |
| EV / EBITDA | N/A | 34.70 |
| FCF yield | N/A | 3.75% |
Profitability
| Metric | DFTX | LFST |
|---|---|---|
| Gross margin | 0.00% | 33.56% |
| Operating margin | 0.00% | 4.95% |
| Net margin | 0.00% | 3.19% |
| ROE | -38.51% | 3.43% |
| ROIC | -23.81% | 3.03% |
Growth (annualized)
| Metric | DFTX | LFST |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 24.79% |
| Total return CAGR (5Y) | 1.43% | -1.46% |
Frequently asked
- Is DFTX or LFST more profitable?
- LFST runs the higher net margin — DFTX at 0.00% versus LFST at 3.19%.
- How have DFTX and LFST total returns compared?
- Over the past 5 years, DFTX delivered 1.43% and LFST delivered -1.46% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
LifeStance Health P/E ratioDefinium Therapeutics ROELifeStance Health ROEDefinium Therapeutics operating marginLifeStance Health operating marginDefinium Therapeutics revenue growthLifeStance Health revenue growthDefinium Therapeutics free cash flowLifeStance Health free cash flow
Definium Therapeutics & LifeStance Health appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.