Cue Biopharma, Inc. (CUE) vs Organogenesis Holdings Inc. (ORGO)

A side-by-side comparison of Cue Biopharma, Inc. and Organogenesis Holdings Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — CUE vs ORGO

growth of $100 · dividends reinvested · last 9y
CUE -93.0% (-25.6%/yr)ORGO -87.0% (-20.3%/yr)ORGO compounded faster over this window
05001k2kStart $10020182020202220242026$7$13
CUE ORGO

CUE vs ORGO: by the numbers

  • •CUE is the larger company ($176M vs $169M market cap).
  • •Both run net losses; ORGO's is the smaller (-19.76% vs -435.83% net margin).
  • •CUE grew revenue faster over the past five years (47.08% vs 1.05% CAGR).

Metrics side by side

Valuation

MetricCUEORGO
P/S ratio4.680.37
P/B ratio76.261.14
EV / EBITDAN/A213.31
FCF yieldN/A12.32%

Profitability

MetricCUEORGO
Gross margin99.69%67.59%
Operating margin-96.56%9.92%
Net margin-435.83%-19.76%
ROE-7104.24%-31.32%
ROIC-1039.56%-8.34%

Growth (annualized)

MetricCUEORGO
Revenue CAGR (5Y)47.08%1.05%
FCF CAGR (5Y)N/A-5.54%
Total return CAGR (5Y)-42.42%-37.41%

Frequently asked

Which has grown faster, CUE or ORGO?
Over the past five years, CUE grew revenue faster — CUE at a 47.08% CAGR versus ORGO at 1.05%.
How have CUE and ORGO total returns compared?
Over the past 5 years, CUE delivered -42.42% and ORGO delivered -37.41% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.