Castle Biosciences, Inc. (CSTL) vs Immatics N.V. (IMTX)
A side-by-side comparison of Castle Biosciences, Inc. and Immatics N.V. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CSTL
Castle Biosciences, Inc.
$34.19HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
IMTX
Immatics N.V.
$7.77HealthcareDelayed quote: Oct 6, 2026, 11:55 AM EDT
Total return — CSTL vs IMTX
growth of $100 · dividends reinvested · last 7yCSTL +71.3% (+8.0%/yr)IMTX -22.6% (-3.6%/yr)CSTL compounded faster over this window
CSTL IMTX
CSTL vs IMTX: by the numbers
- •CSTL is the larger company ($1.04B vs $1.04B market cap).
- •Both run net losses; CSTL's is the smaller (-5.43% vs -493.26% net margin).
- •CSTL grew revenue faster over the past five years (35.55% vs 6.40% CAGR).
Metrics side by side
Valuation
| Metric | CSTL | IMTX |
|---|---|---|
| P/S ratio | 2.92 | 21.46 |
| P/B ratio | 2.22 | 2.28 |
Profitability
| Metric | CSTL | IMTX |
|---|---|---|
| Gross margin | 77.26% | 100.00% |
| Operating margin | -8.99% | -377.11% |
| Net margin | -5.43% | -493.26% |
| ROE | -4.13% | -52.47% |
| ROIC | -6.33% | -53.36% |
Growth (annualized)
| Metric | CSTL | IMTX |
|---|---|---|
| Revenue CAGR (5Y) | 35.55% | 6.40% |
| Total return CAGR (5Y) | -10.28% | -9.88% |
Frequently asked
- Which has grown faster, CSTL or IMTX?
- Over the past five years, CSTL grew revenue faster — CSTL at a 35.55% CAGR versus IMTX at 6.40%.
- How have CSTL and IMTX total returns compared?
- Over the past 5 years, CSTL delivered -10.28% and IMTX delivered -9.88% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Castle Biosciences ROEImmatics ROECastle Biosciences operating marginImmatics operating marginCastle Biosciences revenue growthImmatics revenue growthCastle Biosciences free cash flowImmatics free cash flow
Castle Biosciences & Immatics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.