Castle Biosciences, Inc. (CSTL) vs GoodRx Holdings, Inc. (GDRX)
A side-by-side comparison of Castle Biosciences, Inc. and GoodRx Holdings, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CSTL
Castle Biosciences, Inc.
$34.14HealthcareDelayed quote: Oct 6, 2026, 10:40 AM EDT
GDRX
GoodRx Holdings, Inc.
$3.33HealthcareDelayed quote: Oct 6, 2026, 10:40 AM EDT
Total return — CSTL vs GDRX
growth of $100 · dividends reinvested · last 6yCSTL -27.1% (-5.1%/yr)GDRX -93.3% (-36.3%/yr)CSTL compounded faster over this window
Log scale — wide-divergence pair
CSTL GDRX
CSTL vs GDRX: by the numbers
- •GDRX is the larger company ($1.16B vs $1.04B market cap).
- •GDRX is profitable (2.07% net margin) while CSTL runs a net loss (-5.43%).
- •CSTL grew revenue faster over the past five years (35.55% vs 4.47% CAGR).
Metrics side by side
Valuation
| Metric | CSTL | GDRX |
|---|---|---|
| P/E ratio | N/A | 78.42 |
| P/S ratio | 2.92 | 1.47 |
| P/B ratio | 2.22 | 1.78 |
| EV / EBITDA | N/A | 8.27 |
| FCF yield | N/A | 12.62% |
Profitability
| Metric | CSTL | GDRX |
|---|---|---|
| Gross margin | 77.26% | 88.05% |
| Operating margin | -8.99% | 10.25% |
| Net margin | -5.43% | 2.07% |
| ROE | -4.13% | 2.51% |
| ROIC | -6.33% | 3.72% |
Growth (annualized)
| Metric | CSTL | GDRX |
|---|---|---|
| Revenue CAGR (5Y) | 35.55% | 4.47% |
| FCF CAGR (5Y) | N/A | 11.72% |
| Total return CAGR (5Y) | -10.28% | -39.98% |
Frequently asked
- Which has grown faster, CSTL or GDRX?
- Over the past five years, CSTL grew revenue faster — CSTL at a 35.55% CAGR versus GDRX at 4.47%.
- Is CSTL or GDRX more profitable?
- GDRX runs the higher net margin — CSTL at -5.43% versus GDRX at 2.07%.
- How have CSTL and GDRX total returns compared?
- Over the past 5 years, CSTL delivered -10.28% and GDRX delivered -39.98% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
GoodRx P/E ratioCastle Biosciences ROEGoodRx ROECastle Biosciences operating marginGoodRx operating marginCastle Biosciences revenue growthGoodRx revenue growthCastle Biosciences free cash flowGoodRx free cash flow
Castle Biosciences & GoodRx appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.