CRISPR Therapeutics AG (CRSP) vs Sotera Health Company (SHC)
A side-by-side comparison of CRISPR Therapeutics AG and Sotera Health Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CRSP
CRISPR Therapeutics AG
$54.59HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT
SHC
Sotera Health Company
$18.39HealthcareDelayed quote: Oct 6, 2026, 2:20 PM EDT
Total return — CRSP vs SHC
growth of $100 · dividends reinvested · last 6yCRSP -47.5% (-10.2%/yr)SHC -26.1% (-4.9%/yr)SHC compounded faster over this window
CRSP SHC
CRSP vs SHC: by the numbers
- •CRSP is the larger company ($5.27B vs $5.24B market cap).
- •SHC is profitable (13.44% net margin) while CRSP runs a net loss (-3368.72%).
- •CRSP grew revenue faster over the past five years (37.32% vs 6.66% CAGR).
Metrics side by side
Valuation
| Metric | CRSP | SHC |
|---|---|---|
| P/E ratio | N/A | 32.12 |
| Forward P/E | N/A | 18.68 |
| P/S ratio | 393.16 | 4.31 |
| P/B ratio | 3.01 | 7.88 |
| EV / EBITDA | N/A | 12.49 |
| FCF yield | N/A | 2.15% |
Profitability
| Metric | CRSP | SHC |
|---|---|---|
| Gross margin | -6537.01% | 54.72% |
| Operating margin | -16191.40% | 36.24% |
| Net margin | -3368.72% | 13.44% |
| ROE | -25.83% | 24.56% |
| ROIC | -21.12% | 8.80% |
Growth (annualized)
| Metric | CRSP | SHC |
|---|---|---|
| Revenue CAGR (5Y) | 37.32% | 6.66% |
| FCF CAGR (5Y) | N/A | 17.34% |
| Total return CAGR (5Y) | -10.97% | -6.39% |
Frequently asked
- Which has grown faster, CRSP or SHC?
- Over the past five years, CRSP grew revenue faster — CRSP at a 37.32% CAGR versus SHC at 6.66%.
- Is CRSP or SHC more profitable?
- SHC runs the higher net margin — CRSP at -3368.72% versus SHC at 13.44%.
- How have CRSP and SHC total returns compared?
- Over the past 5 years, CRSP delivered -10.97% and SHC delivered -6.39% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Sotera Health P/E ratioCRISPR Therapeutics AG ROESotera Health ROECRISPR Therapeutics AG operating marginSotera Health operating marginCRISPR Therapeutics AG revenue growthSotera Health revenue growthCRISPR Therapeutics AG free cash flowSotera Health free cash flow
CRISPR Therapeutics AG & Sotera Health appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.