CRISPR Therapeutics AG (CRSP) vs Sotera Health Company (SHC)

A side-by-side comparison of CRISPR Therapeutics AG and Sotera Health Company across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — CRSP vs SHC

growth of $100 · dividends reinvested · last 6y
CRSP -47.5% (-10.2%/yr)SHC -26.1% (-4.9%/yr)SHC compounded faster over this window
50100150Start $100202120222023202420252026$52$74
CRSP SHC

CRSP vs SHC: by the numbers

  • •CRSP is the larger company ($5.27B vs $5.24B market cap).
  • •SHC is profitable (13.44% net margin) while CRSP runs a net loss (-3368.72%).
  • •CRSP grew revenue faster over the past five years (37.32% vs 6.66% CAGR).

Metrics side by side

Valuation

MetricCRSPSHC
P/E ratioN/A32.12
Forward P/EN/A18.68
P/S ratio393.164.31
P/B ratio3.017.88
EV / EBITDAN/A12.49
FCF yieldN/A2.15%

Profitability

MetricCRSPSHC
Gross margin-6537.01%54.72%
Operating margin-16191.40%36.24%
Net margin-3368.72%13.44%
ROE-25.83%24.56%
ROIC-21.12%8.80%

Growth (annualized)

MetricCRSPSHC
Revenue CAGR (5Y)37.32%6.66%
FCF CAGR (5Y)N/A17.34%
Total return CAGR (5Y)-10.97%-6.39%

Frequently asked

Which has grown faster, CRSP or SHC?
Over the past five years, CRSP grew revenue faster — CRSP at a 37.32% CAGR versus SHC at 6.66%.
Is CRSP or SHC more profitable?
SHC runs the higher net margin — CRSP at -3368.72% versus SHC at 13.44%.
How have CRSP and SHC total returns compared?
Over the past 5 years, CRSP delivered -10.97% and SHC delivered -6.39% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.