CRISPR Therapeutics AG (CRSP) vs Iovance Biotherapeutics, Inc. (IOVA)
A side-by-side comparison of CRISPR Therapeutics AG and Iovance Biotherapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CRSP
CRISPR Therapeutics AG
$54.09HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
IOVA
Iovance Biotherapeutics, Inc.
$13.28HealthcareDelayed quote: Oct 6, 2026, 12:00 PM EDT
Total return — CRSP vs IOVA
growth of $100 · dividends reinvested · last 10yCRSP +307.0% (+15.1%/yr)IOVA +122.8% (+8.3%/yr)CRSP compounded faster over this window
CRSP IOVA
CRSP vs IOVA: by the numbers
- •IOVA is the larger company ($5.93B vs $5.22B market cap).
- •Both run net losses; IOVA's is the smaller (-89.09% vs -3368.72% net margin).
Metrics side by side
Valuation
| Metric | CRSP | IOVA |
|---|---|---|
| P/S ratio | 389.52 | 18.24 |
| P/B ratio | 2.99 | 8.05 |
Profitability
| Metric | CRSP | IOVA |
|---|---|---|
| Gross margin | -6537.01% | 97.23% |
| Operating margin | -16191.40% | -153.08% |
| Net margin | -3368.72% | -89.09% |
| ROE | -25.83% | -39.33% |
| ROIC | -21.12% | -37.26% |
Growth (annualized)
| Metric | CRSP | IOVA |
|---|---|---|
| Revenue CAGR (5Y) | 37.32% | N/A |
| Total return CAGR (5Y) | -10.97% | -11.55% |
Frequently asked
- How have CRSP and IOVA total returns compared?
- Over the past 5 years, CRSP delivered -10.97% and IOVA delivered -11.55% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
CRISPR Therapeutics AG ROEIovance Biotherapeutics ROECRISPR Therapeutics AG operating marginIovance Biotherapeutics operating marginCRISPR Therapeutics AG revenue growthIovance Biotherapeutics revenue growthCRISPR Therapeutics AG free cash flowIovance Biotherapeutics free cash flow
CRISPR Therapeutics AG & Iovance Biotherapeutics appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.