CRISPR Therapeutics AG (CRSP) vs Definium Therapeutics, Inc. (DFTX)

A side-by-side comparison of CRISPR Therapeutics AG and Definium Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — CRSP vs DFTX

growth of $100 · dividends reinvested · last 10y
CRSP +225.8% (+12.5%/yr)DFTX +971.9% (+26.8%/yr)DFTX compounded faster over this window
05001k2k2kStart $10020182020202220242026$326$1,072
CRSP DFTX

CRSP vs DFTX: by the numbers

  • •CRSP is the larger company ($5.27B vs $4.68B market cap).
  • •Both run net losses; DFTX's is the smaller (0.00% vs -3368.72% net margin).

Metrics side by side

Valuation

MetricCRSPDFTX
P/S ratio393.16N/A
P/B ratio3.015.09

Profitability

MetricCRSPDFTX
Gross margin-6537.01%0.00%
Operating margin-16191.40%0.00%
Net margin-3368.72%0.00%
ROE-25.83%-38.51%
ROIC-21.12%-23.81%

Growth (annualized)

MetricCRSPDFTX
Revenue CAGR (5Y)37.32%N/A
Total return CAGR (5Y)-10.97%1.43%

Frequently asked

How have CRSP and DFTX total returns compared?
Over the past 5 years, CRSP delivered -10.97% and DFTX delivered 1.43% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.