Cronos Group Inc. (CRON) vs Castle Biosciences, Inc. (CSTL)
A side-by-side comparison of Cronos Group Inc. and Castle Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CRON
Cronos Group Inc.
$3.26HealthcareDelayed quote: Oct 6, 2026, 9:30 AM EDT
CSTL
Castle Biosciences, Inc.
$36.74HealthcareDelayed quote: Oct 6, 2026, 9:30 AM EDT
Total return — CRON vs CSTL
growth of $100 · dividends reinvested · last 7yCRON -78.9% (-19.9%/yr)CSTL +71.3% (+8.0%/yr)CSTL compounded faster over this window
Log scale — wide-divergence pair
CRON CSTL
CRON vs CSTL: by the numbers
- •CRON is the larger company ($1.22B vs $1.12B market cap).
- •CRON is profitable (30.98% net margin) while CSTL runs a net loss (-5.43%).
- •CSTL grew revenue faster over the past five years (35.55% vs 31.80% CAGR).
Metrics side by side
Valuation
| Metric | CRON | CSTL |
|---|---|---|
| P/E ratio | 18.00 | N/A |
| P/S ratio | 5.41 | 3.14 |
| P/B ratio | 1.14 | 2.39 |
| EV / EBITDA | 27.74 | N/A |
| FCF yield | 4.08% | N/A |
Profitability
| Metric | CRON | CSTL |
|---|---|---|
| Gross margin | 36.16% | 77.26% |
| Operating margin | -11.96% | -8.99% |
| Net margin | 30.98% | -5.43% |
| ROE | 6.53% | -4.13% |
| ROIC | 1.12% | -6.33% |
Growth (annualized)
| Metric | CRON | CSTL |
|---|---|---|
| Revenue CAGR (5Y) | 31.80% | 35.55% |
| Total return CAGR (5Y) | -9.92% | -10.28% |
Frequently asked
- Which has grown faster, CRON or CSTL?
- Over the past five years, CSTL grew revenue faster — CRON at a 31.80% CAGR versus CSTL at 35.55%.
- Is CRON or CSTL more profitable?
- CRON runs the higher net margin — CRON at 30.98% versus CSTL at -5.43%.
- How have CRON and CSTL total returns compared?
- Over the past 5 years, CRON delivered -9.92% and CSTL delivered -10.28% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Cronos P/E ratioCronos ROECastle Biosciences ROECronos operating marginCastle Biosciences operating marginCronos revenue growthCastle Biosciences revenue growthCronos free cash flowCastle Biosciences free cash flow
Cronos & Castle Biosciences appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.