Which has the lower trailing P/E, CRMD or IRWD?

CRMD has the lower trailing P/E: CRMD trades at 3.37 and IRWD at 4.74. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, CRMD or IRWD?

Over the past five years, CRMD grew revenue faster — CRMD at a 352.03% CAGR versus IRWD at -1.18%.

Is CRMD or IRWD more profitable?

CRMD runs the higher net margin — CRMD at 40.49% versus IRWD at 33.36%.

How have CRMD and IRWD total returns compared?

Over the past 10 years, CRMD delivered -7.74% and IRWD delivered -13.70% annualized total return. Past performance doesn't predict future results.

CorMedix Inc. (CRMD) vs Ironwood Pharmaceuticals, Inc. (IRWD)

A side-by-side comparison of CorMedix Inc. and Ironwood Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

CRMD

CorMedix Inc.

$564M

$7.19HealthcareDelayed quote: Oct 6, 2026, 11:05 AM EDT

IRWD

Ironwood Pharmaceuticals, Inc.

$598M

$3.64HealthcareDelayed quote: Oct 6, 2026, 11:00 AM EDT

Total return — CRMD vs IRWD

growth of $100 · dividends reinvested · last 10y

CRMD -48.3% (-6.4%/yr)IRWD -77.1% (-13.7%/yr)CRMD compounded faster over this window

CRMD IRWD

CRMD vs IRWD: by the numbers

•IRWD is the larger company ($598M vs $564M market cap).
•CRMD trades at the lower trailing earnings multiple (3.37 vs 4.74 P/E), one valuation lens rather than an overall verdict.
•CRMD converts more revenue to profit (40.49% vs 33.36% net margin).
•CRMD grew revenue faster over the past five years (352.03% vs -1.18% CAGR).

Metrics side by side

Valuation

Metric	CRMD	IRWD
P/E ratio	3.37	4.74
Forward P/E	14.52	2.97
P/S ratio	1.22	1.54
P/B ratio	1.22	N/A
EV / EBITDA	1.79	3.85
FCF yield	44.40%	31.01%

Profitability

Metric	CRMD	IRWD
Gross margin	82.78%	99.76%
Operating margin	46.95%	40.10%
Net margin	40.49%	33.36%
ROE	40.62%	N/A
ROIC	27.87%	58.60%

Growth (annualized)

Metric	CRMD	IRWD
Revenue CAGR (5Y)	352.03%	-1.18%
EPS CAGR (5Y)	N/A	-25.87%
FCF CAGR (5Y)	N/A	-3.98%
Total return CAGR (5Y)	9.70%	-22.82%

Frequently asked

Which has the lower trailing P/E, CRMD or IRWD?: CRMD has the lower trailing P/E: CRMD trades at 3.37 and IRWD at 4.74. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, CRMD or IRWD?: Over the past five years, CRMD grew revenue faster — CRMD at a 352.03% CAGR versus IRWD at -1.18%.
Is CRMD or IRWD more profitable?: CRMD runs the higher net margin — CRMD at 40.49% versus IRWD at 33.36%.
How have CRMD and IRWD total returns compared?: Over the past 10 years, CRMD delivered -7.74% and IRWD delivered -13.70% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CRMD analysis Full IRWD analysis Interactive comparison tool

Dig into the metrics

CorMedix P/E ratio Ironwood Pharmaceuticals P/E ratio CorMedix ROE Ironwood Pharmaceuticals ROE CorMedix operating margin Ironwood Pharmaceuticals operating margin CorMedix revenue growth Ironwood Pharmaceuticals revenue growth CorMedix free cash flow Ironwood Pharmaceuticals free cash flow

CorMedix & Ironwood Pharmaceuticals appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.