Which has grown faster, CRL or TMDX?

Over the past five years, TMDX grew revenue faster — CRL at a 5.77% CAGR versus TMDX at 90.79%.

Is CRL or TMDX more profitable?

TMDX runs the higher net margin — CRL at -4.59% versus TMDX at 27.04%.

Which has been the better investment, CRL or TMDX?

Over the past 5-year, TMDX delivered the higher annualized total return — CRL at 8.46% versus TMDX at 21.48%. Past performance doesn't predict future results.

Charles River Laboratories International, Inc. (CRL) vs TransMedics Group, Inc. (TMDX)

TMDX leads on 9 of 12 compared metrics.

A side-by-side comparison of Charles River Laboratories International, Inc. and TransMedics Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 20, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

CRL

Charles River Laboratories International, Inc.

$8.91B

$185.00Healthcare

TMDX

TransMedics Group, Inc.

$2.72B

$78.79Healthcare

Total return — CRL vs TMDX

growth of $100 · last 7y

CRL +32.4%TMDX +252.4%TMDX compounded faster

CRL TMDX

CRL vs TMDX: by the numbers

•CRL is the larger company ($8.91B vs $2.72B market cap).
•TMDX is profitable (27.04% net margin) while CRL runs a net loss (-4.59%).
•TMDX grew revenue faster over the past five years (90.79% vs 5.77% CAGR).

Which is better, CRL or TMDX?

Metric tally: CRL 3 · TMDX 9

It depends on what you're optimizing for:

GrowthTMDX(faster 5Y revenue CAGR)

QualityTMDX(higher ROIC)

Metrics side by side

Valuation

Metric	CRL	TMDX
P/E ratio	—	18.03
Forward P/E	14.99●	38.89
P/S ratio	2.25●	4.48
P/B ratio	3.08●	5.77
PEG ratio	—	0.05
EV / EBITDA	41.03	23.28●
FCF yield	4.32%	5.31%●

Profitability

Metric	CRL	TMDX
Gross margin	31.86%	59.09%●
Operating margin	11.77%	14.85%●
Net margin	-4.59%	27.04%●
ROE	-6.28%	34.80%●
ROIC	8.36%	10.94%●

Growth (annualized)

Metric	CRL	TMDX
Revenue CAGR (5Y)	5.77%	90.79%●
EPS CAGR (5Y)	-40.99%	—
FCF CAGR (5Y)	-3.98%	—
Total return CAGR (5Y)	-12.16%	21.48%●

Frequently asked

Which is better, CRL or TMDX?: It depends on your goal. growth: TMDX (faster 5Y revenue CAGR); quality: TMDX (higher ROIC). Across all compared metrics, TMDX leads 9 to 3.
Which has grown faster, CRL or TMDX?: Over the past five years, TMDX grew revenue faster — CRL at a 5.77% CAGR versus TMDX at 90.79%.
Is CRL or TMDX more profitable?: TMDX runs the higher net margin — CRL at -4.59% versus TMDX at 27.04%.
Which has been the better investment, CRL or TMDX?: Over the past 5-year, TMDX delivered the higher annualized total return — CRL at 8.46% versus TMDX at 21.48%. Past performance doesn't predict future results.

Go deeper

Full CRL analysis Full TMDX analysis Interactive comparison tool

Dig into the metrics

Charles River Laboratories International P/E ratio TransMedics P/E ratio Charles River Laboratories International dividend yield TransMedics dividend yield Charles River Laboratories International ROE TransMedics ROE Charles River Laboratories International operating margin TransMedics operating margin Charles River Laboratories International revenue growth TransMedics revenue growth Charles River Laboratories International free cash flow TransMedics free cash flow

Charles River Laboratories International & TransMedics appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 20, 2026.