Charles River Laboratories International, Inc. (CRL) vs Shoulder Innovations, Inc. (SI)
CRL leads on 5 of 7 compared metrics.
A side-by-side comparison of Charles River Laboratories International, Inc. and Shoulder Innovations, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 21, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).
CRL
Charles River Laboratories International, Inc.
$185.00Healthcare
SI
Shoulder Innovations, Inc.
$18.55Healthcare
Total return — CRL vs SI
growth of $100 · last 1yCRL +9.1%SI +23.3%SI compounded faster
CRL SI
CRL vs SI: by the numbers
- •CRL is the larger company ($8.91B vs $385M market cap).
- •Both run net losses; CRL's is the smaller (-4.59% vs -81.78% net margin).
Metrics side by side
Valuation
| Metric | CRL | SI |
|---|---|---|
| Forward P/E | 15.01 | — |
| P/S ratio | 2.25● | 7.11 |
| P/B ratio | 3.08 | 2.88● |
| EV / EBITDA | 41.03 | — |
| FCF yield | 4.32% | — |
Profitability
| Metric | CRL | SI |
|---|---|---|
| Gross margin | 31.86% | 75.48%● |
| Operating margin | 11.77%● | -57.48% |
| Net margin | -4.59%● | -81.78% |
| ROE | -6.28%● | -33.14% |
| ROIC | 8.36%● | -14.80% |
Growth (annualized)
| Metric | CRL | SI |
|---|---|---|
| Revenue CAGR (5Y) | 5.77% | — |
| EPS CAGR (5Y) | -40.99% | — |
| FCF CAGR (5Y) | -3.98% | — |
| Total return CAGR (5Y) | -12.16% | — |
Go deeper
Dig into the metrics
Charles River Laboratories International P/E ratioShoulder Innovations P/E ratioCharles River Laboratories International dividend yieldShoulder Innovations dividend yieldCharles River Laboratories International ROEShoulder Innovations ROECharles River Laboratories International operating marginShoulder Innovations operating marginCharles River Laboratories International revenue growthShoulder Innovations revenue growthCharles River Laboratories International free cash flowShoulder Innovations free cash flow
Charles River Laboratories International & Shoulder Innovations appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 21, 2026.