Which has grown faster, CRL or HSIC?

Over the past five years, CRL grew revenue faster — CRL at a 5.77% CAGR versus HSIC at 4.74%.

Is CRL or HSIC more profitable?

HSIC runs the higher net margin — CRL at -4.59% versus HSIC at 2.95%.

Which has been the better investment, CRL or HSIC?

Over the past 10-year, CRL delivered the higher annualized total return — CRL at 8.10% versus HSIC at 1.38%. Past performance doesn't predict future results.

Charles River Laboratories International, Inc. (CRL) vs Henry Schein, Inc. (HSIC)

HSIC leads on 8 of 13 compared metrics.

A side-by-side comparison of Charles River Laboratories International, Inc. and Henry Schein, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of June 23, 2026. The ● marks the stronger figure on each row (cheaper multiple, higher margin/return).

CRL

Charles River Laboratories International, Inc.

Total return — CRL vs HSIC

growth of $100 · last 26y

CRL +725.3%HSIC +2277.6%HSIC compounded faster

CRL HSIC

CRL vs HSIC: by the numbers

•HSIC is the larger company ($8.96B vs $8.75B market cap).
•HSIC is profitable (2.95% net margin) while CRL runs a net loss (-4.59%).
•CRL grew revenue faster over the past five years (5.77% vs 4.74% CAGR).

Which is better, CRL or HSIC?

Metric tally: CRL 5 · HSIC 8

It depends on what you're optimizing for:

GrowthCRL(faster 5Y revenue CAGR)

QualityCRL(higher ROIC)

Metrics side by side

Valuation

Metric	CRL	HSIC
P/E ratio	—	23.77
Forward P/E	14.73	14.71
P/S ratio	2.21	0.68●
P/B ratio	3.02	2.80●
PEG ratio	—	3.23
EV / EBITDA	40.45	12.72●
FCF yield	4.40%	4.72%●

Profitability

Metric	CRL	HSIC
Gross margin	31.86%●	29.69%
Operating margin	11.77%●	5.60%
Net margin	-4.59%	2.95%●
ROE	-6.28%	12.09%●
ROIC	8.36%●	6.58%

Growth (annualized)

Metric	CRL	HSIC
Revenue CAGR (5Y)	5.77%●	4.74%
EPS CAGR (5Y)	-40.99%	-0.74%●
FCF CAGR (5Y)	-3.98%●	-4.53%
Total return CAGR (5Y)	-12.99%	0.58%●

Frequently asked

Which is better, CRL or HSIC?: It depends on your goal. growth: CRL (faster 5Y revenue CAGR); quality: CRL (higher ROIC). Across all compared metrics, HSIC leads 8 to 5.
Which has grown faster, CRL or HSIC?: Over the past five years, CRL grew revenue faster — CRL at a 5.77% CAGR versus HSIC at 4.74%.
Is CRL or HSIC more profitable?: HSIC runs the higher net margin — CRL at -4.59% versus HSIC at 2.95%.
Which has been the better investment, CRL or HSIC?: Over the past 10-year, CRL delivered the higher annualized total return — CRL at 8.10% versus HSIC at 1.38%. Past performance doesn't predict future results.

Go deeper

Full CRL analysis Full HSIC analysis Interactive comparison tool

Dig into the metrics

Charles River Laboratories International P/E ratio Henry Schein P/E ratio Charles River Laboratories International dividend yield Henry Schein dividend yield Charles River Laboratories International ROE Henry Schein ROE Charles River Laboratories International operating margin Henry Schein operating margin Charles River Laboratories International revenue growth Henry Schein revenue growth Charles River Laboratories International free cash flow Henry Schein free cash flow

Charles River Laboratories International & Henry Schein appear in these rankings

Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified June 23, 2026.