Caribou Biosciences, Inc. (CRBU) vs LENZ Therapeutics, Inc. (LENZ)

A side-by-side comparison of Caribou Biosciences, Inc. and LENZ Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — CRBU vs LENZ

growth of $100 · dividends reinvested · last 5y
CRBU -92.7% (-40.8%/yr)LENZ -93.6% (-42.3%/yr)CRBU compounded faster over this window
050100150Start $10020222023202420252026$7$6
CRBU LENZ

CRBU vs LENZ: by the numbers

  • •LENZ is the larger company ($119M vs $113M market cap).
  • •Both run net losses; LENZ's is the smaller (-586.74% vs -1030.42% net margin).

Metrics side by side

Valuation

MetricCRBULENZ
P/S ratio11.225.53
P/B ratio1.150.54

Profitability

MetricCRBULENZ
Gross margin67.34%90.14%
Operating margin-1220.49%-477.46%
Net margin-1030.42%-586.74%
ROE-105.40%-57.47%
ROIC-87.72%-61.84%

Growth (annualized)

MetricCRBULENZ
Revenue CAGR (5Y)-2.03%N/A
Total return CAGR (5Y)-44.43%-35.49%

Frequently asked

How have CRBU and LENZ total returns compared?
Over the past 5 years, CRBU delivered -44.43% and LENZ delivered -35.49% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.