Which has grown faster, COO or TWST?

Over the past five years, TWST grew revenue faster — COO at a 8.29% CAGR versus TWST at 27.77%.

Is COO or TWST more profitable?

COO runs the higher net margin — COO at 13.46% versus TWST at -31.66%.

How have COO and TWST total returns compared?

Over the past 5 years, COO delivered -11.35% and TWST delivered 15.59% annualized total return. Past performance doesn't predict future results.

The Cooper Companies, Inc. (COO) vs Twist Bioscience Corporation (TWST)

A side-by-side comparison of The Cooper Companies, Inc. and Twist Bioscience Corporation across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

COO

The Cooper Companies, Inc.

$10.97B

$56.27HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT

TWST

Twist Bioscience Corporation

$10.55B

$169.38HealthcareDelayed quote: Oct 6, 2026, 3:05 PM EDT

Total return — COO vs TWST

growth of $100 · dividends reinvested · last 8y

COO -10.4% (-1.4%/yr)TWST +1364.3% (+39.9%/yr)TWST compounded faster over this window

Log scale — wide-divergence pair

COO TWST

COO vs TWST: by the numbers

•COO is the larger company ($10.97B vs $10.55B market cap).
•COO is profitable (13.46% net margin) while TWST runs a net loss (-31.66%).
•TWST grew revenue faster over the past five years (27.77% vs 8.29% CAGR).

Metrics side by side

Valuation

Metric	COO	TWST
P/E ratio	19.20	N/A
Forward P/E	12.39	N/A
P/S ratio	2.59	24.43
P/B ratio	1.32	23.66
EV / EBITDA	14.39	N/A
FCF yield	6.18%	N/A

Profitability

Metric	COO	TWST
Gross margin	63.64%	51.97%
Operating margin	12.85%	-31.91%
Net margin	13.46%	-31.66%
ROE	6.85%	-30.67%
ROIC	4.76%	-24.57%

Growth (annualized)

Metric	COO	TWST
Revenue CAGR (5Y)	8.29%	27.77%
EPS CAGR (5Y)	-17.30%	N/A
FCF CAGR (5Y)	5.21%	N/A
Total return CAGR (5Y)	-11.35%	15.59%

Frequently asked

Which has grown faster, COO or TWST?: Over the past five years, TWST grew revenue faster — COO at a 8.29% CAGR versus TWST at 27.77%.
Is COO or TWST more profitable?: COO runs the higher net margin — COO at 13.46% versus TWST at -31.66%.
How have COO and TWST total returns compared?: Over the past 5 years, COO delivered -11.35% and TWST delivered 15.59% annualized total return. Past performance doesn't predict future results.

Go deeper

Full COO analysis Full TWST analysis Interactive comparison tool

Dig into the metrics

Cooper Companies P/E ratio Cooper Companies ROE Twist Bioscience ROE Cooper Companies operating margin Twist Bioscience operating margin Cooper Companies revenue growth Twist Bioscience revenue growth Cooper Companies free cash flow Twist Bioscience free cash flow

Cooper Companies & Twist Bioscience appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.