The Cooper Companies, Inc. (COO) vs Madrigal Pharmaceuticals, Inc. (MDGL)

A side-by-side comparison of The Cooper Companies, Inc. and Madrigal Pharmaceuticals, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
The Cooper Companies, Inc. logo
COO
The Cooper Companies, Inc.
$10.98B
$56.30HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT
Madrigal Pharmaceuticals, Inc. logo
MDGL
Madrigal Pharmaceuticals, Inc.
$11.46B
$496.22HealthcareDelayed quote: Oct 6, 2026, 3:30 PM EDT

Total return — COO vs MDGL

growth of $100 · dividends reinvested · last 10y
COO +29.2% (+2.6%/yr)MDGL +2930.2% (+40.7%/yr)MDGL compounded faster over this window
Log scale — wide-divergence pair
101001k10kStart $10020182020202220242026$129$3,030
COO MDGL

COO vs MDGL: by the numbers

  • •MDGL is the larger company ($11.46B vs $10.98B market cap).
  • •COO is profitable (13.46% net margin) while MDGL runs a net loss (-25.32%).

Metrics side by side

Valuation

MetricCOOMDGL
P/E ratio19.21N/A
Forward P/E12.39N/A
P/S ratio2.598.93
P/B ratio1.3221.89
EV / EBITDA14.40N/A
FCF yield6.18%N/A

Profitability

MetricCOOMDGL
Gross margin63.64%91.48%
Operating margin12.85%-25.13%
Net margin13.46%-25.32%
ROE6.85%-62.07%
ROIC4.76%-37.02%

Growth (annualized)

MetricCOOMDGL
Revenue CAGR (5Y)8.29%N/A
EPS CAGR (5Y)-17.30%N/A
FCF CAGR (5Y)5.21%N/A
Total return CAGR (5Y)-11.35%44.41%

Frequently asked

Is COO or MDGL more profitable?
COO runs the higher net margin — COO at 13.46% versus MDGL at -25.32%.
How have COO and MDGL total returns compared?
Over the past 10 years, COO delivered 2.53% and MDGL delivered 41.50% annualized total return. Past performance doesn't predict future results.

Go deeper

Full COO analysisFull MDGL analysisInteractive comparison tool

Dig into the metrics

Cooper Companies P/E ratioCooper Companies ROEMadrigal Pharmaceuticals ROECooper Companies operating marginMadrigal Pharmaceuticals operating marginCooper Companies revenue growthMadrigal Pharmaceuticals revenue growthCooper Companies free cash flowMadrigal Pharmaceuticals free cash flow

Cooper Companies & Madrigal Pharmaceuticals appear in these rankings

Highest FCF Yield StocksHighest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.