Which has the lower trailing P/E, COLL or MDXG?

COLL has the lower trailing P/E: COLL trades at 17.65 and MDXG at 115.50. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, COLL or MDXG?

Over the past five years, COLL grew revenue faster — COLL at a 19.91% CAGR versus MDXG at 6.36%.

Is COLL or MDXG more profitable?

COLL runs the higher net margin — COLL at 5.93% versus MDXG at 1.76%.

How have COLL and MDXG total returns compared?

Over the past 10 years, COLL delivered 1.39% and MDXG delivered -6.46% annualized total return. Past performance doesn't predict future results.

Collegium Pharmaceutical, Inc. (COLL) vs MiMedx Group, Inc. (MDXG)

A side-by-side comparison of Collegium Pharmaceutical, Inc. and MiMedx Group, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

COLL

Collegium Pharmaceutical, Inc.

$710M

$21.88HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

MDXG

MiMedx Group, Inc.

$673M

$4.62HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — COLL vs MDXG

growth of $100 · dividends reinvested · last 10y

COLL +14.8% (+1.4%/yr)MDXG -47.0% (-6.1%/yr)COLL compounded faster over this window

COLL MDXG

COLL vs MDXG: by the numbers

•COLL is the larger company ($710M vs $673M market cap).
•COLL trades at the lower trailing earnings multiple (17.65 vs 115.50 P/E), one valuation lens rather than an overall verdict.
•COLL converts more revenue to profit (5.93% vs 1.76% net margin).
•COLL grew revenue faster over the past five years (19.91% vs 6.36% CAGR).

Metrics side by side

Valuation

Metric	COLL	MDXG
P/E ratio	17.65	115.50
PEG ratio	0.99	N/A
P/S ratio	0.88	1.90
P/B ratio	2.28	3.12
EV / EBITDA	2.84	26.41
FCF yield	46.26%	6.03%

Profitability

Metric	COLL	MDXG
Gross margin	60.02%	78.85%
Operating margin	19.61%	15.26%
Net margin	5.93%	1.76%
ROE	15.36%	2.89%
ROIC	6.11%	1.97%

Growth (annualized)

Metric	COLL	MDXG
Revenue CAGR (5Y)	19.91%	6.36%
EPS CAGR (5Y)	20.48%	N/A
FCF CAGR (5Y)	26.38%	N/A
Total return CAGR (5Y)	2.15%	-4.94%

Frequently asked

Which has the lower trailing P/E, COLL or MDXG?: COLL has the lower trailing P/E: COLL trades at 17.65 and MDXG at 115.50. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, COLL or MDXG?: Over the past five years, COLL grew revenue faster — COLL at a 19.91% CAGR versus MDXG at 6.36%.
Is COLL or MDXG more profitable?: COLL runs the higher net margin — COLL at 5.93% versus MDXG at 1.76%.
How have COLL and MDXG total returns compared?: Over the past 10 years, COLL delivered 1.39% and MDXG delivered -6.46% annualized total return. Past performance doesn't predict future results.

Go deeper

Full COLL analysis Full MDXG analysis Interactive comparison tool

Dig into the metrics

Collegium Pharmaceutical P/E ratio MiMedx P/E ratio Collegium Pharmaceutical ROE MiMedx ROE Collegium Pharmaceutical operating margin MiMedx operating margin Collegium Pharmaceutical revenue growth MiMedx revenue growth Collegium Pharmaceutical free cash flow MiMedx free cash flow

Collegium Pharmaceutical & MiMedx appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.