Which has grown faster, COLL or FDMT?

Over the past five years, FDMT grew revenue faster — COLL at a 19.91% CAGR versus FDMT at 31.93%.

Is COLL or FDMT more profitable?

COLL runs the higher net margin — COLL at 5.93% versus FDMT at -194.74%.

How have COLL and FDMT total returns compared?

Over the past 5 years, COLL delivered 2.15% and FDMT delivered -13.08% annualized total return. Past performance doesn't predict future results.

Collegium Pharmaceutical, Inc. (COLL) vs 4D Molecular Therapeutics, Inc. (FDMT)

A side-by-side comparison of Collegium Pharmaceutical, Inc. and 4D Molecular Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

COLL

Collegium Pharmaceutical, Inc.

$709M

$21.87HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT

FDMT

4D Molecular Therapeutics, Inc.

$660M

$12.63HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT

Total return — COLL vs FDMT

growth of $100 · dividends reinvested · last 6y

COLL +15.0% (+2.4%/yr)FDMT -68.1% (-17.3%/yr)COLL compounded faster over this window

COLL FDMT

COLL vs FDMT: by the numbers

•COLL is the larger company ($709M vs $660M market cap).
•COLL is profitable (5.93% net margin) while FDMT runs a net loss (-194.74%).
•FDMT grew revenue faster over the past five years (31.93% vs 19.91% CAGR).

Metrics side by side

Valuation

Metric	COLL	FDMT
P/E ratio	17.64	N/A
PEG ratio	0.99	N/A
P/S ratio	0.88	7.18
P/B ratio	2.27	1.62
EV / EBITDA	2.84	N/A
FCF yield	46.28%	N/A

Profitability

Metric	COLL	FDMT
Gross margin	60.02%	91.05%
Operating margin	19.61%	-187.24%
Net margin	5.93%	-194.74%
ROE	15.36%	-43.95%
ROIC	6.11%	-44.30%

Growth (annualized)

Metric	COLL	FDMT
Revenue CAGR (5Y)	19.91%	31.93%
EPS CAGR (5Y)	20.48%	N/A
FCF CAGR (5Y)	26.38%	N/A
Total return CAGR (5Y)	2.15%	-13.08%

Frequently asked

Which has grown faster, COLL or FDMT?: Over the past five years, FDMT grew revenue faster — COLL at a 19.91% CAGR versus FDMT at 31.93%.
Is COLL or FDMT more profitable?: COLL runs the higher net margin — COLL at 5.93% versus FDMT at -194.74%.
How have COLL and FDMT total returns compared?: Over the past 5 years, COLL delivered 2.15% and FDMT delivered -13.08% annualized total return. Past performance doesn't predict future results.

Go deeper

Full COLL analysis Full FDMT analysis Interactive comparison tool

Dig into the metrics

Collegium Pharmaceutical P/E ratio Collegium Pharmaceutical ROE 4D Molecular Therapeutics ROE Collegium Pharmaceutical operating margin 4D Molecular Therapeutics operating margin Collegium Pharmaceutical revenue growth 4D Molecular Therapeutics revenue growth Collegium Pharmaceutical free cash flow 4D Molecular Therapeutics free cash flow

Collegium Pharmaceutical & 4D Molecular Therapeutics appear in these rankings

Fastest Revenue Growth Stocks Highest FCF Yield Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.