How have COGT and PTCT total returns compared?

Over the past 5 years, COGT delivered 28.51% and PTCT delivered 11.75% annualized total return. Past performance doesn't predict future results.

Cogent Biosciences, Inc. (COGT) vs PTC Therapeutics, Inc. (PTCT)

A side-by-side comparison of Cogent Biosciences, Inc. and PTC Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

COGT

Cogent Biosciences, Inc.

$5.18B

$30.33HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT

PTCT

PTC Therapeutics, Inc.

$5.31B

$63.64HealthcareDelayed quote: Oct 6, 2026, 1:00 PM EDT

Total return — COGT vs PTCT

growth of $100 · dividends reinvested · last 9y

COGT -30.5% (-4.0%/yr)PTCT +99.4% (+8.0%/yr)PTCT compounded faster over this window

COGT PTCT

COGT vs PTCT: by the numbers

•PTCT is the larger company ($5.31B vs $5.18B market cap).
•Both run net losses; COGT's is the smaller (0.00% vs -3.80% net margin).

Metrics side by side

Valuation

Metric	COGT	PTCT
Forward P/E	N/A	50.08
P/S ratio	N/A	5.27
P/B ratio	11.08	N/A
EV / EBITDA	N/A	28.90

Profitability

Metric	COGT	PTCT
Gross margin	0.00%	95.85%
Operating margin	0.00%	49.49%
Net margin	0.00%	-3.80%
ROE	-70.85%	N/A
ROIC	-50.09%	4.59%

Growth (annualized)

Metric	COGT	PTCT
Revenue CAGR (5Y)	N/A	16.41%
Total return CAGR (5Y)	28.51%	11.75%

Frequently asked

How have COGT and PTCT total returns compared?: Over the past 5 years, COGT delivered 28.51% and PTCT delivered 11.75% annualized total return. Past performance doesn't predict future results.

Go deeper

Full COGT analysis Full PTCT analysis Interactive comparison tool

Dig into the metrics

Cogent Biosciences ROE PTC Therapeutics ROE Cogent Biosciences operating margin PTC Therapeutics operating margin Cogent Biosciences revenue growth PTC Therapeutics revenue growth Cogent Biosciences free cash flow PTC Therapeutics free cash flow

Cogent Biosciences & PTC Therapeutics appear in these rankings

Fastest Revenue Growth Stocks Highest Operating Margin Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.