Cogent Biosciences, Inc. (COGT) vs Kiniksa Pharmaceuticals International, plc (KNSA)

A side-by-side comparison of Cogent Biosciences, Inc. and Kiniksa Pharmaceuticals International, plc across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

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Total return — COGT vs KNSA

growth of $100 · dividends reinvested · last 8y
COGT -32.7% (-4.8%/yr)KNSA +291.9% (+18.6%/yr)KNSA compounded faster over this window
Log scale — wide-divergence pair
1101001kStart $1002020202220242026$67$392
COGT KNSA

COGT vs KNSA: by the numbers

  • •KNSA is the larger company ($5.65B vs $5.13B market cap).
  • •KNSA is profitable (9.59% net margin) while COGT runs a net loss (0.00%).

Metrics side by side

Valuation

MetricCOGTKNSA
P/E ratioN/A75.60
Forward P/EN/A53.20
P/S ratioN/A6.71
P/B ratio10.978.63
EV / EBITDAN/A53.70
FCF yieldN/A3.24%

Profitability

MetricCOGTKNSA
Gross margin0.00%54.49%
Operating margin0.00%11.92%
Net margin0.00%9.59%
ROE-70.85%12.33%
ROIC-50.09%9.76%

Growth (annualized)

MetricCOGTKNSA
Revenue CAGR (5Y)N/A155.66%
Total return CAGR (5Y)28.51%47.48%

Frequently asked

Is COGT or KNSA more profitable?
KNSA runs the higher net margin — COGT at 0.00% versus KNSA at 9.59%.
How have COGT and KNSA total returns compared?
Over the past 5 years, COGT delivered 28.51% and KNSA delivered 47.48% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.