Cogent Biosciences, Inc. (COGT) vs Definium Therapeutics, Inc. (DFTX)

A side-by-side comparison of Cogent Biosciences, Inc. and Definium Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare

Total return — COGT vs DFTX

growth of $100 · dividends reinvested · last 9y
COGT -30.5% (-4.0%/yr)DFTX +1510.2% (+36.2%/yr)DFTX compounded faster over this window
Log scale — wide-divergence pair
01101001k10kStart $1002020202220242026$69$1,610
COGT DFTX

COGT vs DFTX: by the numbers

  • •COGT is the larger company ($5.09B vs $4.62B market cap).

Metrics side by side

Valuation

MetricCOGTDFTX
P/B ratio10.895.03

Profitability

MetricCOGTDFTX
Gross margin0.00%0.00%
Operating margin0.00%0.00%
Net margin0.00%0.00%
ROE-70.85%-38.51%
ROIC-50.09%-23.81%

Growth (annualized)

MetricCOGTDFTX
Total return CAGR (5Y)28.51%1.43%

Frequently asked

How have COGT and DFTX total returns compared?
Over the past 5 years, COGT delivered 28.51% and DFTX delivered 1.43% annualized total return. Past performance doesn't predict future results.

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.