ClearPoint Neuro, Inc. (CLPT) vs Orchestra BioMed Holdings, Inc. (OBIO)
A side-by-side comparison of ClearPoint Neuro, Inc. and Orchestra BioMed Holdings, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CLPT
ClearPoint Neuro, Inc.
$11.00HealthcareDelayed quote: Oct 6, 2026, 12:05 PM EDT
OBIO
Orchestra BioMed Holdings, Inc.
$5.88HealthcareDelayed quote: Oct 6, 2026, 11:59 AM EDT
Total return — CLPT vs OBIO
growth of $100 · dividends reinvested · last 6yCLPT +142.5% (+15.9%/yr)OBIO -47.1% (-10.1%/yr)CLPT compounded faster over this window
CLPT OBIO
CLPT vs OBIO: by the numbers
- •OBIO is the larger company ($352M vs $330M market cap).
- •Both run net losses; CLPT's is the smaller (-81.76% vs -184.60% net margin).
- •OBIO grew revenue faster over the past five years (148.45% vs 23.57% CAGR).
Metrics side by side
Valuation
| Metric | CLPT | OBIO |
|---|---|---|
| P/S ratio | 7.80 | 11.02 |
| P/B ratio | 30.61 | 18.23 |
Profitability
| Metric | CLPT | OBIO |
|---|---|---|
| Gross margin | 62.61% | 99.32% |
| Operating margin | -65.36% | -154.73% |
| Net margin | -81.76% | -184.60% |
| ROE | -320.77% | -200.64% |
| ROIC | -40.51% | -56.73% |
Growth (annualized)
| Metric | CLPT | OBIO |
|---|---|---|
| Revenue CAGR (5Y) | 23.57% | 148.45% |
| Total return CAGR (5Y) | -7.65% | -9.35% |
Frequently asked
- Which has grown faster, CLPT or OBIO?
- Over the past five years, OBIO grew revenue faster — CLPT at a 23.57% CAGR versus OBIO at 148.45%.
- How have CLPT and OBIO total returns compared?
- Over the past 5 years, CLPT delivered -7.65% and OBIO delivered -9.35% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
ClearPoint Neuro ROEOrchestra BioMed ROEClearPoint Neuro operating marginOrchestra BioMed operating marginClearPoint Neuro revenue growthOrchestra BioMed revenue growthClearPoint Neuro free cash flowOrchestra BioMed free cash flow
ClearPoint Neuro & Orchestra BioMed appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.