Celldex Therapeutics, Inc. (CLDX) vs Inspire Medical Systems, Inc. (INSP)
A side-by-side comparison of Celldex Therapeutics, Inc. and Inspire Medical Systems, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CLDX
Celldex Therapeutics, Inc.
$32.59HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
INSP
Inspire Medical Systems, Inc.
$70.75HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
Total return — CLDX vs INSP
growth of $100 · dividends reinvested · last 8yCLDX +175.0% (+13.5%/yr)INSP +183.2% (+13.9%/yr)INSP compounded faster over this window
CLDX INSP
CLDX vs INSP: by the numbers
- •CLDX is the larger company ($2.17B vs $2.05B market cap).
- •INSP is profitable (15.03% net margin) while CLDX runs a net loss (-268385.71%).
- •INSP grew revenue faster over the past five years (38.69% vs -58.05% CAGR).
Metrics side by side
Valuation
| Metric | CLDX | INSP |
|---|---|---|
| P/E ratio | N/A | 15.31 |
| Forward P/E | N/A | 59.24 |
| P/S ratio | 19361.50 | 2.28 |
| P/B ratio | 3.03 | 2.48 |
| EV / EBITDA | N/A | 27.29 |
| FCF yield | N/A | 5.72% |
Profitability
| Metric | CLDX | INSP |
|---|---|---|
| Gross margin | 100.00% | 86.13% |
| Operating margin | -19160.00% | 6.02% |
| Net margin | -268385.71% | 15.03% |
| ROE | -42.07% | 16.36% |
| ROIC | -45.19% | 6.33% |
Growth (annualized)
| Metric | CLDX | INSP |
|---|---|---|
| Revenue CAGR (5Y) | -58.05% | 38.69% |
| Total return CAGR (5Y) | -10.28% | -21.38% |
Frequently asked
- Which has grown faster, CLDX or INSP?
- Over the past five years, INSP grew revenue faster — CLDX at a -58.05% CAGR versus INSP at 38.69%.
- Is CLDX or INSP more profitable?
- INSP runs the higher net margin — CLDX at -268385.71% versus INSP at 15.03%.
- How have CLDX and INSP total returns compared?
- Over the past 5 years, CLDX delivered -10.28% and INSP delivered -21.38% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Inspire Medical Systems P/E ratioCelldex Therapeutics ROEInspire Medical Systems ROECelldex Therapeutics operating marginInspire Medical Systems operating marginCelldex Therapeutics revenue growthInspire Medical Systems revenue growthCelldex Therapeutics free cash flowInspire Medical Systems free cash flow
Celldex Therapeutics & Inspire Medical Systems appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.