Compugen Ltd. (CGEN) vs Sionna Therapeutics, Inc. (SION)

A side-by-side comparison of Compugen Ltd. and Sionna Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
Compugen Ltd. logo
CGEN
Compugen Ltd.
$210M
$2.22HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT
Sionna Therapeutics, Inc. logo
SION
Sionna Therapeutics, Inc.
$214M
$4.75HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — CGEN vs SION

growth of $100 · dividends reinvested · last 2y
CGEN -1.7% (-0.9%/yr)SION -80.6% (-56.0%/yr)CGEN compounded faster over this window
Log scale — wide-divergence pair
101001kStart $1002026$98$19
CGEN SION

CGEN vs SION: by the numbers

  • •SION is the larger company ($214M vs $210M market cap).
  • •CGEN is profitable (47.55% net margin) while SION runs a net loss (0.00%).

Metrics side by side

Valuation

MetricCGENSION
P/E ratio5.91N/A
P/S ratio2.84N/A
P/B ratio2.370.81

Profitability

MetricCGENSION
Gross margin86.89%0.00%
Operating margin40.94%0.00%
Net margin47.55%0.00%
ROE39.66%-36.64%
ROIC26.14%-40.18%

Growth (annualized)

MetricCGENSION
Revenue CAGR (5Y)105.91%N/A
Total return CAGR (5Y)-18.39%N/A

Frequently asked

Is CGEN or SION more profitable?
CGEN runs the higher net margin — CGEN at 47.55% versus SION at 0.00%.

Go deeper

Full CGEN analysisFull SION analysisInteractive comparison tool

Dig into the metrics

Compugen P/E ratioCompugen ROESionna Therapeutics ROECompugen operating marginSionna Therapeutics operating marginCompugen revenue growthSionna Therapeutics revenue growthCompugen free cash flowSionna Therapeutics free cash flow

Compugen & Sionna Therapeutics appear in these rankings

Fastest Revenue Growth StocksHighest ROE StocksHighest ROIC StocksHighest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.