Is CGEN or NAUT more profitable?

CGEN runs the higher net margin — CGEN at 47.55% versus NAUT at -29747.89%.

How have CGEN and NAUT total returns compared?

Over the past 5 years, CGEN delivered -18.39% and NAUT delivered -20.56% annualized total return. Past performance doesn't predict future results.

Compugen Ltd. (CGEN) vs Nautilus Biotechnolgy, Inc. (NAUT)

A side-by-side comparison of Compugen Ltd. and Nautilus Biotechnolgy, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

CGEN

Compugen Ltd.

$216M

$2.28HealthcareDelayed quote: Oct 6, 2026, 11:31 AM EDT

NAUT

Nautilus Biotechnolgy, Inc.

$249M

$1.95HealthcareDelayed quote: Oct 6, 2026, 11:25 AM EDT

Total return — CGEN vs NAUT

growth of $100 · dividends reinvested · last 6y

CGEN -85.9% (-27.8%/yr)NAUT -82.1% (-24.9%/yr)NAUT compounded faster over this window

CGEN NAUT

CGEN vs NAUT: by the numbers

•NAUT is the larger company ($249M vs $216M market cap).
•CGEN is profitable (47.55% net margin) while NAUT runs a net loss (-29747.89%).

Metrics side by side

Valuation

Metric	CGEN	NAUT
P/E ratio	6.07	N/A
P/S ratio	2.91	1307.92
P/B ratio	2.43	1.90

Profitability

Metric	CGEN	NAUT
Gross margin	86.89%	0.00%
Operating margin	40.94%	0.00%
Net margin	47.55%	-29747.89%
ROE	39.66%	-43.11%
ROIC	26.14%	-40.52%

Growth (annualized)

Metric	CGEN	NAUT
Revenue CAGR (5Y)	105.91%	N/A
Total return CAGR (5Y)	-18.39%	-20.56%

Frequently asked

Is CGEN or NAUT more profitable?: CGEN runs the higher net margin — CGEN at 47.55% versus NAUT at -29747.89%.
How have CGEN and NAUT total returns compared?: Over the past 5 years, CGEN delivered -18.39% and NAUT delivered -20.56% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CGEN analysis Full NAUT analysis Interactive comparison tool

Dig into the metrics

Compugen P/E ratio Compugen ROE Nautilus Biotechnolgy ROE Compugen operating margin Nautilus Biotechnolgy operating margin Compugen revenue growth Nautilus Biotechnolgy revenue growth Compugen free cash flow Nautilus Biotechnolgy free cash flow

Compugen & Nautilus Biotechnolgy appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.