Which has grown faster, CGEN or LYEL?

Over the past five years, CGEN grew revenue faster — CGEN at a 105.91% CAGR versus LYEL at -68.32%.

Is CGEN or LYEL more profitable?

CGEN runs the higher net margin — CGEN at 47.55% versus LYEL at -920285.19%.

How have CGEN and LYEL total returns compared?

Over the past 5 years, CGEN delivered -18.39% and LYEL delivered -48.18% annualized total return. Past performance doesn't predict future results.

Compugen Ltd. (CGEN) vs Lyell Immunopharma, Inc. (LYEL)

A side-by-side comparison of Compugen Ltd. and Lyell Immunopharma, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

CGEN

Compugen Ltd.

$212M

$2.24HealthcareDelayed quote: Oct 6, 2026, 1:59 PM EDT

LYEL

Lyell Immunopharma, Inc.

$214M

$8.75HealthcareDelayed quote: Oct 6, 2026, 1:55 PM EDT

Total return — CGEN vs LYEL

growth of $100 · dividends reinvested · last 5y

CGEN -69.6% (-21.2%/yr)LYEL -97.3% (-51.5%/yr)CGEN compounded faster over this window

Log scale — wide-divergence pair

CGEN LYEL

CGEN vs LYEL: by the numbers

•LYEL is the larger company ($214M vs $212M market cap).
•CGEN is profitable (47.55% net margin) while LYEL runs a net loss (-920285.19%).
•CGEN grew revenue faster over the past five years (105.91% vs -68.32% CAGR).

Metrics side by side

Valuation

Metric	CGEN	LYEL
P/E ratio	5.97	N/A
P/S ratio	2.86	7941.23
P/B ratio	2.39	0.92

Profitability

Metric	CGEN	LYEL
Gross margin	86.89%	-31952.78%
Operating margin	40.94%	-566038.89%
Net margin	47.55%	-920285.19%
ROE	39.66%	-106.27%
ROIC	26.14%	-70.80%

Growth (annualized)

Metric	CGEN	LYEL
Revenue CAGR (5Y)	105.91%	-68.32%
Total return CAGR (5Y)	-18.39%	-48.18%

Frequently asked

Which has grown faster, CGEN or LYEL?: Over the past five years, CGEN grew revenue faster — CGEN at a 105.91% CAGR versus LYEL at -68.32%.
Is CGEN or LYEL more profitable?: CGEN runs the higher net margin — CGEN at 47.55% versus LYEL at -920285.19%.
How have CGEN and LYEL total returns compared?: Over the past 5 years, CGEN delivered -18.39% and LYEL delivered -48.18% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CGEN analysis Full LYEL analysis Interactive comparison tool

Dig into the metrics

Compugen P/E ratio Compugen ROE Lyell Immunopharma ROE Compugen operating margin Lyell Immunopharma operating margin Compugen revenue growth Lyell Immunopharma revenue growth Compugen free cash flow Lyell Immunopharma free cash flow

Compugen & Lyell Immunopharma appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Highest Operating Margin Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.