Is CGEM or MGTX more profitable?

MGTX runs the higher net margin — CGEM at 0.00% versus MGTX at 19.87%.

How have CGEM and MGTX total returns compared?

Over the past 5 years, CGEM delivered -7.48% and MGTX delivered -3.10% annualized total return. Past performance doesn't predict future results.

Cullinan Therapeutics, Inc. (CGEM) vs MeiraGTx Holdings plc (MGTX)

A side-by-side comparison of Cullinan Therapeutics, Inc. and MeiraGTx Holdings plc across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

CGEM

Cullinan Therapeutics, Inc.

$999M

$16.25HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

MGTX

MeiraGTx Holdings plc

$982M

$10.60HealthcareDelayed quote: Oct 6, 2026, 4:00 PM EDT

Total return — CGEM vs MGTX

growth of $100 · dividends reinvested · last 6y

CGEM -46.4% (-9.9%/yr)MGTX -33.5% (-6.6%/yr)MGTX compounded faster over this window

CGEM MGTX

CGEM vs MGTX: by the numbers

•CGEM is the larger company ($999M vs $982M market cap).
•MGTX is profitable (19.87% net margin) while CGEM runs a net loss (0.00%).

Metrics side by side

Valuation

Metric	CGEM	MGTX
P/E ratio	N/A	14.93
Forward P/E	N/A	35.33
P/S ratio	N/A	2.47
P/B ratio	3.10	4.55
EV / EBITDA	N/A	4.84

Profitability

Metric	CGEM	MGTX
Gross margin	0.00%	97.19%
Operating margin	0.00%	-130.20%
Net margin	0.00%	19.87%
ROE	-63.62%	36.64%
ROIC	-68.64%	52.81%

Growth (annualized)

Metric	CGEM	MGTX
Revenue CAGR (5Y)	N/A	84.52%
Total return CAGR (5Y)	-7.48%	-3.10%

Some values include inputs from SEC filing.

Frequently asked

Is CGEM or MGTX more profitable?: MGTX runs the higher net margin — CGEM at 0.00% versus MGTX at 19.87%.
How have CGEM and MGTX total returns compared?: Over the past 5 years, CGEM delivered -7.48% and MGTX delivered -3.10% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CGEM analysis Full MGTX analysis Interactive comparison tool

Dig into the metrics

MeiraGTx P/E ratio Cullinan Therapeutics ROE MeiraGTx ROE Cullinan Therapeutics operating margin MeiraGTx operating margin Cullinan Therapeutics revenue growth MeiraGTx revenue growth Cullinan Therapeutics free cash flow MeiraGTx free cash flow

Cullinan Therapeutics & MeiraGTx appear in these rankings

Fastest Revenue Growth Stocks Highest ROE Stocks Highest ROIC Stocks Lowest P/E Ratio Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.