Cullinan Therapeutics, Inc. (CGEM) vs Castle Biosciences, Inc. (CSTL)
A side-by-side comparison of Cullinan Therapeutics, Inc. and Castle Biosciences, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CGEM
Cullinan Therapeutics, Inc.
$16.49HealthcareDelayed quote: Oct 6, 2026, 3:00 PM EDT
CSTL
Castle Biosciences, Inc.
$33.45HealthcareDelayed quote: Oct 6, 2026, 3:00 PM EDT
Total return — CGEM vs CSTL
growth of $100 · dividends reinvested · last 6yCGEM -46.4% (-9.9%/yr)CSTL -54.0% (-12.1%/yr)CGEM compounded faster over this window
CGEM CSTL
CGEM vs CSTL: by the numbers
- •CSTL is the larger company ($1.02B vs $1.01B market cap).
- •Both run net losses; CGEM's is the smaller (0.00% vs -5.43% net margin).
Metrics side by side
Valuation
| Metric | CGEM | CSTL |
|---|---|---|
| P/S ratio | N/A | 2.86 |
| P/B ratio | 3.15 | 2.17 |
Profitability
| Metric | CGEM | CSTL |
|---|---|---|
| Gross margin | 0.00% | 77.26% |
| Operating margin | 0.00% | -8.99% |
| Net margin | 0.00% | -5.43% |
| ROE | -63.62% | -4.13% |
| ROIC | -68.64% | -6.33% |
Growth (annualized)
| Metric | CGEM | CSTL |
|---|---|---|
| Revenue CAGR (5Y) | N/A | 35.55% |
| Total return CAGR (5Y) | -7.48% | -10.28% |
Frequently asked
- How have CGEM and CSTL total returns compared?
- Over the past 5 years, CGEM delivered -7.48% and CSTL delivered -10.28% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
Cullinan Therapeutics ROECastle Biosciences ROECullinan Therapeutics operating marginCastle Biosciences operating marginCullinan Therapeutics revenue growthCastle Biosciences revenue growthCullinan Therapeutics free cash flowCastle Biosciences free cash flow
Cullinan Therapeutics & Castle Biosciences appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.