CareDx, Inc (CDNA) vs iRhythm Technologies, Inc. (IRTC)
A side-by-side comparison of CareDx, Inc and iRhythm Technologies, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.
CDNA
CareDx, Inc
$64.63HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT
IRTC
iRhythm Technologies, Inc.
$107.19HealthcareDelayed quote: Oct 6, 2026, 3:35 PM EDT
Total return — CDNA vs IRTC
growth of $100 · dividends reinvested · last 10yCDNA +1714.3% (+33.6%/yr)IRTC +318.8% (+15.4%/yr)CDNA compounded faster over this window
CDNA IRTC
CDNA vs IRTC: by the numbers
- •IRTC is the larger company ($3.52B vs $3.34B market cap).
- •CDNA is profitable (24.23% net margin) while IRTC runs a net loss (-1.69%).
- •IRTC grew revenue faster over the past five years (21.93% vs 12.56% CAGR).
Metrics side by side
Valuation
| Metric | CDNA | IRTC |
|---|---|---|
| P/E ratio | 31.20 | N/A |
| Forward P/E | 53.95 | N/A |
| P/S ratio | 7.30 | 4.27 |
| P/B ratio | 7.86 | 18.94 |
| EV / EBITDA | 192.12 | 286.34 |
| FCF yield | 2.54% | 1.11% |
Profitability
| Metric | CDNA | IRTC |
|---|---|---|
| Gross margin | 70.58% | 71.45% |
| Operating margin | -0.92% | -1.17% |
| Net margin | 24.23% | -1.69% |
| ROE | 26.08% | -7.50% |
| ROIC | -0.93% | -1.07% |
Growth (annualized)
| Metric | CDNA | IRTC |
|---|---|---|
| Revenue CAGR (5Y) | 12.56% | 21.93% |
| Total return CAGR (5Y) | 1.33% | 12.95% |
Frequently asked
- Which has grown faster, CDNA or IRTC?
- Over the past five years, IRTC grew revenue faster — CDNA at a 12.56% CAGR versus IRTC at 21.93%.
- Is CDNA or IRTC more profitable?
- CDNA runs the higher net margin — CDNA at 24.23% versus IRTC at -1.69%.
- How have CDNA and IRTC total returns compared?
- Over the past 5 years, CDNA delivered 1.33% and IRTC delivered 12.95% annualized total return. Past performance doesn't predict future results.
Go deeper
Dig into the metrics
CareDx P/E ratioCareDx ROEiRhythm Technologies ROECareDx operating marginiRhythm Technologies operating marginCareDx revenue growthiRhythm Technologies revenue growthCareDx free cash flowiRhythm Technologies free cash flow
CareDx & iRhythm Technologies appear in these rankings
Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.