Which has the lower trailing P/E, CDNA or ICUI?

CDNA has the lower trailing P/E: CDNA trades at 32.09 and ICUI at 134.08. P/E is one valuation measure and does not by itself establish which business is cheaper.

Which has grown faster, CDNA or ICUI?

Over the past five years, CDNA grew revenue faster — CDNA at a 12.56% CAGR versus ICUI at 11.05%.

Is CDNA or ICUI more profitable?

CDNA runs the higher net margin — CDNA at 24.23% versus ICUI at 1.39%.

How have CDNA and ICUI total returns compared?

Over the past 10 years, CDNA delivered 34.41% and ICUI delivered 2.51% annualized total return. Past performance doesn't predict future results.

CareDx, Inc (CDNA) vs ICU Medical, Inc. (ICUI)

A side-by-side comparison of CareDx, Inc and ICU Medical, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

CDNA

CareDx, Inc

$3.44B

$66.46HealthcareDelayed quote: Oct 6, 2026, 10:35 AM EDT

ICUI

ICU Medical, Inc.

$3.95B

$158.22HealthcareDelayed quote: Oct 6, 2026, 10:35 AM EDT

Total return — CDNA vs ICUI

growth of $100 · dividends reinvested · last 10y

CDNA +1824.2% (+34.4%/yr)ICUI +28.4% (+2.5%/yr)CDNA compounded faster over this window

Log scale — wide-divergence pair

CDNA ICUI

CDNA vs ICUI: by the numbers

•ICUI is the larger company ($3.95B vs $3.44B market cap).
•CDNA trades at the lower trailing earnings multiple (32.09 vs 134.08 P/E), one valuation lens rather than an overall verdict.
•CDNA converts more revenue to profit (24.23% vs 1.39% net margin).
•CDNA grew revenue faster over the past five years (12.56% vs 11.05% CAGR).

Metrics side by side

Valuation

Metric	CDNA	ICUI
P/E ratio	32.09	134.08
Forward P/E	55.48	N/A
P/S ratio	7.51	1.83
P/B ratio	8.08	1.84
EV / EBITDA	198.20	13.55
FCF yield	2.47%	3.86%

Profitability

Metric	CDNA	ICUI
Gross margin	70.58%	37.56%
Operating margin	-0.92%	5.04%
Net margin	24.23%	1.39%
ROE	26.08%	1.40%
ROIC	-0.93%	3.11%

Growth (annualized)

Metric	CDNA	ICUI
Revenue CAGR (5Y)	12.56%	11.05%
EPS CAGR (5Y)	N/A	-62.79%
FCF CAGR (5Y)	N/A	-2.65%
Total return CAGR (5Y)	1.33%	-7.18%

Frequently asked

Which has the lower trailing P/E, CDNA or ICUI?: CDNA has the lower trailing P/E: CDNA trades at 32.09 and ICUI at 134.08. P/E is one valuation measure and does not by itself establish which business is cheaper.
Which has grown faster, CDNA or ICUI?: Over the past five years, CDNA grew revenue faster — CDNA at a 12.56% CAGR versus ICUI at 11.05%.
Is CDNA or ICUI more profitable?: CDNA runs the higher net margin — CDNA at 24.23% versus ICUI at 1.39%.
How have CDNA and ICUI total returns compared?: Over the past 10 years, CDNA delivered 34.41% and ICUI delivered 2.51% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CDNA analysis Full ICUI analysis Interactive comparison tool

Dig into the metrics

CareDx P/E ratio ICU Medical P/E ratio CareDx ROE ICU Medical ROE CareDx operating margin ICU Medical operating margin CareDx revenue growth ICU Medical revenue growth CareDx free cash flow ICU Medical free cash flow

CareDx & ICU Medical appear in these rankings

Highest ROE Stocks Highest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.