CareDx, Inc (CDNA) vs Edgewise Therapeutics, Inc. (EWTX)

A side-by-side comparison of CareDx, Inc and Edgewise Therapeutics, Inc. across valuation, profitability, dividends, and growth — built entirely from reported fundamentals, as of October 6, 2026. Differences are shown without an overall score or investment verdict.

Compare
CareDx, Inc logo
CDNA
CareDx, Inc
$3.61B
$69.85HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT
Edgewise Therapeutics, Inc. logo
EWTX
Edgewise Therapeutics, Inc.
$4.34B
$40.30HealthcareDelayed quote: Oct 5, 2026, 4:00 PM EDT

Total return — CDNA vs EWTX

growth of $100 · dividends reinvested · last 6y
CDNA +10.1% (+1.6%/yr)EWTX +34.3% (+5.0%/yr)EWTX compounded faster over this window
050100150Start $10020222023202420252026$110$134
CDNA EWTX

CDNA vs EWTX: by the numbers

  • •EWTX is the larger company ($4.34B vs $3.61B market cap).
  • •CDNA is profitable (24.23% net margin) while EWTX runs a net loss (0.00%).

Metrics side by side

Valuation

MetricCDNAEWTX
P/E ratio33.72N/A
Forward P/E58.32N/A
P/S ratio7.89N/A
P/B ratio8.499.68
EV / EBITDA209.49N/A
FCF yield2.35%N/A

Profitability

MetricCDNAEWTX
Gross margin70.58%0.00%
Operating margin-0.92%0.00%
Net margin24.23%0.00%
ROE26.08%-44.02%
ROIC-0.93%-48.57%

Growth (annualized)

MetricCDNAEWTX
Revenue CAGR (5Y)12.56%N/A
Total return CAGR (5Y)1.33%16.95%

Frequently asked

Is CDNA or EWTX more profitable?
CDNA runs the higher net margin — CDNA at 24.23% versus EWTX at 0.00%.
How have CDNA and EWTX total returns compared?
Over the past 5 years, CDNA delivered 1.33% and EWTX delivered 16.95% annualized total return. Past performance doesn't predict future results.

Go deeper

Full CDNA analysisFull EWTX analysisInteractive comparison tool

Dig into the metrics

CareDx P/E ratioCareDx ROEEdgewise Therapeutics ROECareDx operating marginEdgewise Therapeutics operating marginCareDx revenue growthEdgewise Therapeutics revenue growthCareDx free cash flowEdgewise Therapeutics free cash flow

CareDx & Edgewise Therapeutics appear in these rankings

Highest ROE StocksHighest 10-Year Total Return Stocks

Figures are sourced from reported fundamentals and the latest end-of-day price. This comparison is informational only and is not investment advice. Past performance does not predict future results. See our methodology. Compiled by TGMCharts Research · data verified October 6, 2026.